Ligand boric acid

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Basic Ligand Information

Molecular Structure
Picture of boric acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
H3BO3
boric acid
KGBXLFKZBHKPEV-UHFFFAOYSA-N
Synonyms:
boracic acid, Borate, H3BO3

Roles as Enzyme Ligand

Activator in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
exposure of the enzyme to borate buffer of pH 10.0 results in activation of the enzyme
-
activation
-
106.4% activity at 1 mM
-
activates
-

Inhibitor in Enzyme-catalyzed Reactions (49 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibition of borneol oxidation
-
10 mM, 90% inhibition
-
inhibition reversible by potassium
-
competitive
-
slight inhibition
-
16% residual activity at 20 mM
-
partial inhibition
-
inhibitory at 20 mM
-
strong inhibition at pH 8.5, not at pH 7.4
-
boric acid/borate buffer is moderately inhibitory
-

Metals and Ions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
stimulates at 10 mM, 1 mM and 0.1 mM
-

3D Structure of Enzyme-Ligand-Complex (PDB) (14 results)

Enzyme Kinetic Parameters

Ki Value (5 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.02
-
-
0.3
-
-

References & Links

Links to other databases for boric acid

ChEBI
PubChem
ChEBI
PubChem