Ligand colcemid

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Basic Ligand Information

Molecular Structure
Picture of colcemid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C21H25NO5
colcemid
NNJPGOLRFBJNIW-UHFFFAOYSA-N
Synonyms:
Demecolcine

Roles as Enzyme Ligand

Inhibitor in Enzyme-catalyzed Reactions (1 result)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE
microtubule inhibitor, arrests cells in M phase, followed by induction of apotosis, 1 and 5 ng/ml colcemid display only modest cytotoxic effects. 10, 50 and 100 ng/ml induce pronounced cell death as measured by flow cytometry analysis
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Enzyme Kinetic Parameters

References & Links

Links to other databases for colcemid

ChEBI
PubChem
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PubChem