Ligand 1D-myo-inositol 1,2,4,5,6-pentakisphosphate

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Basic Ligand Information

Molecular Structure
Picture of 1D-myo-inositol 1,2,4,5,6-pentakisphosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H17O21P5
1D-myo-inositol 1,2,4,5,6-pentakisphosphate
CTPQAXVNYGZUAJ-XCMZKKERSA-N
Synonyms:
1D-myo-inositol-1,2,4,5,6-pentakisphosphate, D-myo-inositol(1,2,4,5,6)pentakisphosphate, D-myo-inositol 1,2,4,5,6-pentakisphosphate, inositol 1,2,4,5,6-pentakisphosphate, myo-inositol-1,2,4,5,6 pentakisphosphate, myo-inositol-1,2,4,5,6-pentakisphosphate, myo-inositol 1,2,4,5,6-pentakisphosphate, myo-inositol pentakisphosphate
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate + phosphate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
myo-inositol-1,2,4,5,6 pentakisphosphate + H2O = ?
show the reaction diagram
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1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate
show the reaction diagram
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1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate
show the reaction diagram
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1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,4,5,6-tetrakisphosphate + phosphate
show the reaction diagram
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myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = myo-inositol-2,4,5,6 tetrakisphosphate + phosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (17 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
myo-inositol tetrakisphosphate + ATP = myo-inositol pentakisphosphate + ADP
show the reaction diagram
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myo-inositol hexakisphosphate + H2O = D-myo-inositol(1,2,4,5,6)pentakisphosphate + phosphate
show the reaction diagram
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myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + 1D-myo-inositol-1,2,5,6 tetrakisphosphate + phosphate
show the reaction diagram
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myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate + phosphate
show the reaction diagram
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myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate + phosphate
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50 for inositol hexakisphosphate kinase activity is 0.022 mM
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Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.133
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IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.022
-
IC50 for inositol hexakisphosphate kinase activity is 0.022 mM

References & Links

Links to other databases for 1D-myo-inositol 1,2,4,5,6-pentakisphosphate

ChEBI
PubChem
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PubChem