Ligand (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

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Basic Ligand Information

Molecular Structure
Picture of (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H12O8P2
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate
MDSIZRKJVDMQOQ-GORDUTHDSA-N
Synonyms:
(2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate, (E)-4-hydroxy-3-methylbut-2-enyl diphosphate, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate, 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate, 4-hydroxy-3-methyl-2-(E)-butenyl diphosphate, E-1-hydroxy-2-methyl-but-2-enyl-4-diphosphate


Show all pahtways known for Show all BRENDA pathways known for (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized flavodoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin
show the reaction diagram
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4-hydroxy-3-methyl-2-(E)-butenyl diphosphate + ADP = diphosphate + trans-zeatin riboside 5'-diphosphate
show the reaction diagram
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1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + AMP = diphosphate + N6-(4-hydroxy-3-methyl-2-(E)-butyl)adenosine 5'-phosphate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized flavodoxin
show the reaction diagram
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isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized flavodoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H
show the reaction diagram
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3D Structure of Enzyme-Ligand-Complex (PDB) (56 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (11 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

ChEBI
PubChem
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PubChem