Ligand kaempferide

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Basic Ligand Information

Molecular Structure
Picture of kaempferide (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C16H12O6
kaempferide
SQFSKOYWJBQGKQ-UHFFFAOYSA-N
Synonyms:
3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one, 3,5,7-trihydroxy-4'-methoxy-flavone, 3,5,7-trihydroxy-4'-methoxyflavone, 4'-O-methyl kaempferol, 4'-O-methylkaempferol, kaempferid, kaempferol-4'-methylether, kaempferol-4'-O-methylether, kaempferol 4'-monomethylether, kaempferol 4'-monomethyl ether

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + 4'-O-methylkaempferol = S-adenosyl-L-homocysteine + 3,4'-O-dimethylkaempferol
show the reaction diagram
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UDP-alpha-D-glucose + kaempferid = UDP + 7-O-beta-D-glucosylkaempferid
show the reaction diagram
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UDPglucose + kaempferol-4'-O-methylether = UDP + ?
show the reaction diagram
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UDP-alpha-D-xylose + 3,5,7-trihydroxy-4'-methoxyflavone = UDP + 3,5,7-trihydroxy-4'-methoxyflavone 3-O-beta-D-xyloside
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + kaempferide
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50: 15 mM
-
inhibition of p56lck
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IC50: 0.008 mM
-
strong inhibition
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Enzyme Kinetic Parameters

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
15
-
IC50: 15 mM
0.008
-
IC50: 0.008 mM

References & Links

Links to other databases for kaempferide

ChEBI
PubChem
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PubChem