Ligand tRNAGln(CUG)
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Basic Ligand Information
Molecular Structure

C28H36N10O25P4R2
tRNAGln(CUG)
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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ATP + L-glutamate + tRNAGln(CUG) = AMP + diphosphate + L-glutamyl-tRNAGln(CUG)
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Substrate in Enzyme-catalyzed Reactions (2 results)
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ATP + L-glutamate + tRNAGln(CUG) = AMP + diphosphate + L-glutamyl-tRNAGln(CUG)
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ATP + L-glutamine + tRNAGln(CUG) = AMP + diphosphate + L-glutaminyl-tRNAGln(CUG)
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
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0.041
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wild type enzyme, pH and temperature not specified in the publication
KM Value (1 result)
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0.00133
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wild type enzyme, pH and temperature not specified in the publication
References & Links
Literature References (2)
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Deinococcus glutaminyl-tRNA synthetase is a chimer between proteins from an ancient and the modern pathways of aminoacyl-tRNA formation
2007
Deniziak, M.; Sauter, C.; Becker, H.D.; Paulus, C.A.; Giege, R.; Kern, D.
Nucleic Acids Res.
35
1421-1431
Rational design of an evolutionary precursor of glutaminyl-tRNA synthetase
2011
O'Donoghue, P.; Sheppard, K.; Nureki, O.; Soell, D.
Proc. Natl. Acad. Sci. USA
108
20485-20490
Links to other databases for tRNAGln(CUG)