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BRENDA support

Ligand 2-Aminoadenosine

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Basic Ligand Information

Molecular Structure
Picture of 2-Aminoadenosine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H14N6O4
2-Aminoadenosine
ZDTFMPXQUSBYRL-UUOKFMHZSA-N
Synonyms:
2,6-diamino-9-beta-D-ribofuranosylpurine, 2,6-diaminopurine nucleoside, 2,6-diaminopurine ribonucleoside, 2,6-diaminopurine riboside, 9-beta-ribosyl-2,6-diaminopurine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + 2,6-diaminopurine riboside = ADP + 2,6-diaminopurine riboside 5'-phosphate
show the reaction diagram
-
2-aminoadenosine + homocysteine = ?
show the reaction diagram
-
2,6-diamino-9-beta-D-ribofuranosylpurine + H2O = 2,6-diaminopurine + D-ribose
show the reaction diagram
-
2,6-diaminopurine riboside + H2O = guanosine + NH3
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,6-diaminopurine + alpha-D-ribose 1-phosphate = 2,6-diaminopurine ribonucleoside + phosphate
show the reaction diagram
-
2-amino-5'-deoxy-5'-(hydroxyethylthio)adenosine + phosphate = 2-aminoadenosine + 5-hydroxyethylthio-D-ribose 1-phosphate
show the reaction diagram
-
guanosine + 2,6-diaminopurine = guanine + 2,6-diaminopurine ribonucleoside
show the reaction diagram
-
5'-ethylthio-2-aminoadenosine + H2O = 5-ethylthio-D-ribose + 2-aminoadenosine
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.1 mM, 10-90% inhibition
-

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.42
-
pH 5.8, 25ºC

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for 2-Aminoadenosine

ChEBI
PubChem
ChEBI
PubChem