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Ligand phenylglycinenitrile Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C8 H8 N2
phenylglycinenitrile
KAXCEFLQAYFJKV-UHFFFAOYSA-N
N-phenylglycinenitrile, phenyl glycinenitrile
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (3 results)
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phenylglycinenitrile + 2 H2O = phenylglycine + NH3
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phenyl glycinenitrile + H2O = phenylalanine + NH3
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N-phenylglycinenitrile + H2O = ?
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (2 results)
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0.016
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pH 7.4, 70°C, mutant enzyme K96R
0.04
-
pH 7.4, 70°C, wild-type enzyme
KM Value (2 results)
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0.000000009
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pH 7.4, 70°C, mutant enzyme K96R
0.000000024
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pH 7.4, 70°C, wild-type enzyme
References & Links Literature References (3)
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Characterisation of nitrilase and nitrile hydratase biocatalytic systems
2004
Brady, D.; Beeton, A.; Zeevaart, J.; Kgaje, C.; van Rantwijk, F.; Sheldon, R.A.
Appl. Microbiol. Biotechnol.
64
76-85
Purification and characterization of an enantioselective arylacetonitrilase from Pseudomonas putida
2006
Banerjee, A.; Kaul, P.; Banerjee, U.C.
Arch. Microbiol.
184
407-418
The signature amidase from Sulfolobus solfataricus belongs to the CX3C subgroup of enzymes cleaving both amides and nitriles. Ser195 and Cys145 are predicted to be the active site nucleophiles
2005
Cilia, E.; Fabbri, A.; Uriani, M.; Scialdone, G.G., Ammendola, S.
FEBS J.
272
4716-4724
Links to other databases for phenylglycinenitrile
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