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Ligand solasodine

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.4.1.173

solasodine + UDP-glucose = UDP + solasodine 3-beta-D-glucoside

671624

-

2.4.1.173

UDP-glucose + solasodine = UDP + solasodine 3-beta-D-glucoside

671624

-

2.4.1.173

2 entries

Inhibitor in Enzyme-catalyzed Reactions (1 result)

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Show Inhibitors (1 entry)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.8.1.12

compound is an alkaloid scaffold lead in the search for inhibitors

743345

-

Enzyme Kinetic Parameters

K_M Value (2 results)

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Show KM Value (2 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

2.4.1.173

0.003

-

-

671624

2.4.1.173

0.007

-

activity is assayed radiometrically using UDP-[U-14C] glucose, at pH 8.0 and 37°C

671624

2.4.1.173

2 entries

References & Links

Literature References (2)

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Show Reference (2 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

671624

17324374

Molecular cloning and characterization of one member of 3beta-hydroxy sterol glucosyltransferase gene family in Withania somnifera

2007

Sharma, L.K.; Madina, B.R.; Chaturvedi, P.; Sangwan, R.S.; Tuli, R.

Arch. Biochem. Biophys.

460

48-55

743345

26996020

Molecular docking and binding mode analysis of plant alkaloids as in vitro and in silico inhibitors of trypanothione reductase from Trypanosoma cruzi

2016

Argueelles, A.J.; Cordell, G.A.; Maruenda, H.

Nat. Prod. Commun.

11

57-62

Links to other databases for solasodine

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Show Links (1 entry)

ChEBI

PubChem