print visible entries

print all entries

Ligand L-Ala-gamma-D-Glu-L-Lys-D-Ala

Basic Ligand Information

Molecular Structure

close all tables

open all tables

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (4 results)

top print hide

Show Substrate (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.4.14.13

L-Ala-gamma-D-Glu-L-Lys-D-Ala + H2O = L-Ala-D-Glu + L-Lys-D-Ala

729191

-

3.4.17.13

L-Ala-gamma-D-Glu-L-Lys-D-Ala + H2O = ?

667221

-

6.3.2.45

ATP + UDP-N-alpha-D-acetylmuramate + L-Ala-gamma-D-Glu-L-Lys-D-Ala = ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala

674330

-

6.3.2.B2

ATP + L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanine + UDP-MurNAc = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-L-lysyl-D-alanine

728549

-

Product in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.4.17.8

L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala + H2O = L-Ala-D-gamma-Glu-L-Lys-D-Ala + D-Ala

-

-

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (3 results)

top print hide

Show Turnover Number (3 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

3.4.14.13

2.6

-

pH and temperature not specified in the publication

729191

6.3.2.45

0.32

-

pH 8.4, 37°C

674330

6.3.2.B2

0.0017

-

pH 8.4, temperature not specified in the publication, recombinant His-tagged enzyme

728549

K_M Value (2 results)

top print hide

Show KM Value (2 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

3.4.14.13

0.12

-

pH and temperature not specified in the publication

729191

6.3.2.45

3.9

-

pH 8.4, 37°C

674330

References & Links

Literature References (4)

top print hide

Show Reference (4 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

667221

16251288

Identification of a dithiazoline inhibitor of Escherichia coli L,D-carboxypeptidase A

2005

Baum, E.Z.; Crespo-Carbone, S.M.; Foleno, B.; Peng, S.; Hilliard, J.J.; Abbanat, D.; Goldschmidt, R.; Bush, K.

Antimicrob. Agents Chemother.

49

4500-4507

674330

17384195

Biochemical characterization and physiological properties of Escherichia coli UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase

2007

Herve, M.; Boniface, A.; Gobec, S.; Bianot, D.; Mengin-Lecreulx, D.

J. Bacteriol.

189

3987-3995

728549

21445265

Structure and function of the first full-length murein peptide ligase (Mpl) cell wall recycling protein

2011

Das, D.; Herve, M.; Feuerhelm, J.; Farr, C.; Chiu, H.; Elsliger, M.; Knuth, M.; Klock, H.; Miller, M.; Godzik, A.; Lesley, S.; Deacon, A.; Mengin-Lecreulx, D.; Wilson, I.

PLoS ONE

6

e17624

729191

11747447

Evolution of enzymatic activities in the enolase superfamily: functional assignment of unknown proteins in Bacillus subtilis and Escherichia coli as L-Ala-D/L-Glu epimerases

2001

Schmidt, D.M.; Hubbard, B.K.; Gerlt, J.A.

Biochemistry

40

15707-15715

Links to other databases for L-Ala-gamma-D-Glu-L-Lys-D-Ala

top print hide

Show Links (1 entry)

ChEBI

PubChem

-