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Ligand sinapoyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of sinapoyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Molfile
C32H46N7O20P3S
sinapoyl-CoA
RBFUWESMWRUGFY-GSNIOFLCSA-N
Synonyms:
4-sinapoyl-CoA

Related pathways

Pathway Source
Pathways
MetaCyc
glucosinolate biosynthesis from dihomomethionine, glucosinolate biosynthesis from homomethionine, hydroxycinnamate sugar acid ester biosynthesis, hydroxycinnamic acid tyramine amides biosynthesis

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
sinapoyl-CoA + NADPH + H+ = sinapaldehyde + CoA + NADP+
show the reaction diagram
-
sinapoyl-CoA + glucarolactone = CoA + O-sinapoylglucarolactone
show the reaction diagram
-
2 sinapoyl-CoA + spermidine = 2 CoA + N1,N8-bis(sinapoyl)-spermidine
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
sinapaldehyde + CoA + NADP+ = sinapoyl-CoA + NADPH + H+
show the reaction diagram
-
-
S-adenosyl-L-methionine + 5-hydroxy-feruloyl-CoA = S-adenosyl-L-homocysteine + sinapoyl-CoA
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (23 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + sinapoyl-CoA = S-adenosyl-L-homocysteine + ?
show the reaction diagram
-
sinapoyl-CoA + tyramine = CoA + sinapoyltyramine
show the reaction diagram
-
sinapoyl-CoA + isocitric acid = CoA + sinapoylisocitric acid
show the reaction diagram
-
sinapoyl-CoA + galactarate = CoA + O-sinapoylgalactarate
show the reaction diagram
-
sinapoyl-CoA + glucarate = CoA + O-sinapoylglucarate
show the reaction diagram
-
sinapoyl-CoA + glucarolactone = CoA + O-sinapoylglucarolactone
show the reaction diagram
-
sinapoyl-CoA + putrescine = CoA + N-sinapoylputrescine
show the reaction diagram
-
sinapoyl-CoA + 3-(4-hydroxyphenyl)lactate = CoA + 2-O-sinapoyl-3-(4-hydroxyphenyl)lactate
show the reaction diagram
-
sinapoyl-CoA + 16-hydroxypalmitic acid = CoA + (E)-16-(3-(4-hydroxy-3,5-dimethoxyphenyl)acryloyloxy)hexadecanoic acid
show the reaction diagram
-
sinapoyl-CoA + agmatine = CoA + sinapoyl agmatine
show the reaction diagram
-
sinapoyl-CoA + quinate = CoA + 5-O-sinapoylquinate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
sinapaldehyde + CoA + NADP+ = sinapoyl-CoA + NADPH + H+
show the reaction diagram
-
-
2 CoA + N1,N8-bis(sinapoyl)-spermidine = 2 sinapoyl-CoA + spermidine
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive inhibitor
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (19 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
5.1
-
pH 7.3, 30°C, recombinant His6-tagged enzyme

KM Value (36 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.018
-
-
0.029
-
-
0.02
-
pH 7.0, 30°C, with shikimate
0.0083
-
pH 7.3, 30°C, recombinant His6-tagged enzyme
0.05
-
-

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.02
-
competitive inhibition of sinapoyl-CoA on the feruloyl-CoA reaction

References & Links

Links to other databases for sinapoyl-CoA

EXTERNAL LINKS