Ligand 4-methyl-L-phenylalanine

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Basic Ligand Information

Molecular Structure
Picture of 4-methyl-L-phenylalanine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H13NO2
4-methyl-L-phenylalanine
DQLHSFUMICQIMB-VIFPVBQESA-N
Synonyms:
4'-methyl-alpha-phenylalanine, 4-methylphenylalanine, p-Methylphenylalanine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-methyl-L-phenylalanine + 6-methyltetrahydropterin + O2 = ?
show the reaction diagram
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4-methyl-L-phenylalanine + H2O + NAD+ = 4-methyl-phenylpyruvate + NH3 + NADH
show the reaction diagram
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4-methyl-L-phenylalanine + phenylacetamide = N-[(4-methylphenyl)acetyl]-L-tyrosine + NH3
show the reaction diagram
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4'-methyl-alpha-phenylalanine = 4'-methyl-beta-phenylalanine
show the reaction diagram
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4-methyl-L-phenylalanine = (S)-3-amino-3-(4-methylphenyl)propanoic acid
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-methyl-phenylpyruvate + NH3 + NADH = 4-methyl-L-phenylalanine + H2O + NAD+
show the reaction diagram
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(2E)-4-methyl-cinnamic acid + NH3 = 4-methyl-L-phenylalanine
show the reaction diagram
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3D Structure of Enzyme-Ligand-Complex (PDB) (9 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.013
-
pH 8.0, 31°C, recombinant enzyme

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.163
-
pH 8.0, 31°C, recombinant enzyme

References & Links

Links to other databases for 4-methyl-L-phenylalanine

ChEBI
PubChem
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PubChem