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BRENDA support

Ligand (E)-cinnamoyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of (E)-cinnamoyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C30H42N7O17P3S
(E)-cinnamoyl-CoA
JVNVHNHITFVWIX-KZKUDURGSA-N
Synonyms:
(2E)-3-phenylprop-2-enoyl-CoA, (E)-3-phenylacryloyl-CoA, cinnamoyl-CoA, trans-cinnamoyl-CoA


Show all pahtways known for Show all BRENDA pathways known for (E)-cinnamoyl-CoA

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cinnamoyl-CoA + NADPH + H+ = cinnamaldehyde + CoA + NADP+
show the reaction diagram
-
cinnamoyl-CoA + malonyl-CoA = 3,5-dihydroxystilbene + CoA + CO2
show the reaction diagram
-
2 cinnamoyl-CoA + malonyl-CoA + H2O = 3 CoA + dicinnamoylmethane + 2 CO2
show the reaction diagram
-
(E)-cinnamoyl-CoA + (R)-phenyllactate = (E)-cinnamate + (R)-phenyllactoyl-CoA
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+
show the reaction diagram
-
benzylmalonyl-CoA + O2 = (E)-cinnamoyl-CoA + CO2 + H2O2
show the reaction diagram
-
3-phenylpropionyl-CoA + acceptor = cinnamoyl-CoA + reduced acceptor
show the reaction diagram
-
(R)-3-phenyllactoyl-CoA = (2E)-3-phenylprop-2-enoyl-CoA + H2O
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (44 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cinnamoyl-CoA + NADPH + CO2 + H+ = (2S)2-carboxy-3-phenylpropionyl-CoA + NADP+
show the reaction diagram
-
cinnamoyl-CoA + putrescine = CoA + N-cinnamoylputrescine
show the reaction diagram
-
cinnamoyl-CoA + malonyl-CoA = 3,5-dihydroxystilbene + CoA + CO2
show the reaction diagram
-
3 malonyl-CoA + cinnamoyl-CoA = 4 CoA + 4-hydroxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one + 3 CO2
show the reaction diagram
-
cinnamoyl-CoA + cinnamoyl-diketide-N-acetylcysteamine + H2O = CoA + dicinnamoylmethane + N-acetylcysteamine
show the reaction diagram
-
cinnamoyl-CoA + 5-hydroxyanthranilate = N-cinnamoyl-5-hydroxyanthranilic acid + CoA
show the reaction diagram
-
cinnamoyl-CoA + agmatine = CoA + cinnamoyl agmatine
show the reaction diagram
-
cinnamoyl-CoA + malonyl-CoA = 3,5-dihydroxystilbene + CoA + CO2
show the reaction diagram
-
cinnamoyl-CoA + H2O = cinnamic acid + CoA
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+
show the reaction diagram
-
benzylmalonyl-CoA + O2 = (E)-cinnamoyl-CoA + CO2 + H2O2
show the reaction diagram
-
3-phenylpropionyl-CoA + acceptor = cinnamoyl-CoA + reduced acceptor
show the reaction diagram
-
ATP + trans-cinnamic acid + CoA = AMP + diphosphate + trans-cinnamoyl-CoA
show the reaction diagram
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.9
-
pH 7.7, 22°C, cosustrate: benzyl alcohol

KM Value (22 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.9
-
-
0.0265
-
pH 7.0, 30°C, with shikimate
0.0025
-
with putrescine
0.464
-
pH 7.7, 22°C, cosustrate: benzyl alcohol
0.27
-
pH 7, temperature not specified in the publication
0.0033
-
-
0.003
0.019
cosubstrate phenylpropionate
0.0029
-
at 30°C, in 50 mM Tris/HCl buffer, pH 7.0

References & Links

Links to other databases for (E)-cinnamoyl-CoA

ChEBI
PubChem
ChEBI
PubChem