Ligand 20-hydroxyeicosatetraenoic acid

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Basic Ligand Information

Molecular Structure
Picture of 20-hydroxyeicosatetraenoic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H32O3
20-hydroxyeicosatetraenoic acid
NNDIXBJHNLFJJP-DTLRTWKJSA-N
Synonyms:
(5Z,8Z,11Z,14Z)-20-hydroxy-eicosatetraenoic acid, (5Z,8Z,11Z,14Z)-20-hydroxyeicosa-5,8,11,14-tetraenoic acid, (5Z,8Z,11Z,14Z)-20-hydroxyeicosatetraenoic acid, 20-HETE, 20-hydroxy-5,8,11,14-eicosatetraenoic acid, 20-hydroxyarachidonic acid, 20-hydroxy arachidonic acid, 20-hydroxyicosa-5,8,11,14-tetraenoic acid

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
arachidonic acid + O2 + NADPH = 20-hydroxyeicosatetraenoic acid + H2O + NADP+
show the reaction diagram
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arachidonic acid + [reduced NADPH-hemoprotein reductase] + O2 = 20-hydroxyarachidonic acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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arachidonate + [reduced NADPH-hemoprotein reductase] + O2 = 20-hydroxy-5,8,11,14-eicosatetraenoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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arachidonic acid + NADPH + H+ + O2 = 20-hydroxyeicosatetraenoic acid + NADP+ + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-glucuronate + 20-hydroxyeicosatetraenoic acid = UDP + 20-hydroxyeicosatetraenoyl beta-D-glucuronoside
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
arachidonic acid + [reduced NADPH-hemoprotein reductase] + O2 = 20-hydroxyarachidonic acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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arachidonate + [reduced NADPH-hemoprotein reductase] + O2 = 20-hydroxy-5,8,11,14-eicosatetraenoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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Enzyme Kinetic Parameters

References & Links

Links to other databases for 20-hydroxyeicosatetraenoic acid

ChEBI
PubChem
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PubChem