Ligand N-acetyl-D-galactosamine 4-sulfate
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Basic Ligand Information
Molecular Structure
C6H13NO8S
N-acetyl-D-galactosamine 4-sulfate
CBHWSXKLUOFXOZ-DGPNFKTASA-N
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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N-acetyl-D-galactosamine 4-sulfate + H2O = N-acetyl-D-galactosamine + sulfate
-
Product in Enzyme-catalyzed Reactions (1 result)
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N-acetyl-D-galactosamine 4,6-disulfate + H2O = N-acetyl-D-galactosamine 4-sulfate + sulfate
-
Inhibitor in Enzyme-catalyzed Reactions (2 results)
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Enzyme Kinetic Parameters
IC50 Value (2 results)
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0.1
-
IC50 is above 0.1 mM
0.1
-
IC50 is above 0.1 mM
References & Links
Literature References (5)
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Purification and properties of arylsulfatase B from high- and low-activity mouse strains
1985
Daniel, W.L.; Ruoff, B.M.; Thompson, D.B.
Biochem. Genet.
23
771-786
The common identity of UDP-N-acetylgalactosamine 4-sulfatase, nitrocatechol sulfatase (arylsulfatase), and chondroitin 4-sulfatase
1980
Tsuji, M.; Nakanishi, Y.; Habuchi, H.; Ishihara, K.; Suzuki, S.
Biochim. Biophys. Acta
612
373-383
Separation and properties of five glycosaminoglycan sulfatases from rat skin
1979
Habuchi, H.; Tsuji, M.; Nakanishi, Y.; Suzuki, S.
J. Biol. Chem.
254
7570-7578
Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble poxide hydrolase
2005
Tran, K.L.; Aronov, P.A.; Tanaka, H.; Newman, J.W.; Hammock, B.D.; Morisseau, C.
Biochemistry
44
12179-12187
Arylsulfatase B regulates colonic epithelial cell migration by effects on MMP9 expression and RhoA activation
2009
Bhattacharyya, S.; Tobacman, J.K.
Clin. Exp. Metastasis
26
535-545
Links to other databases for N-acetyl-D-galactosamine 4-sulfate
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