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BRENDA support

Ligand 5-sulfosalicylic acid

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Basic Ligand Information

Molecular Structure
Picture of 5-sulfosalicylic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H6O6S
5-sulfosalicylic acid
YCPXWRQRBFJBPZ-UHFFFAOYSA-N
Synonyms:
5-sulfosalicylate, sulfosalicylate, sulfosalicylic acid, sulfurosalicylic acid
Pathway Source
Pathways

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
sulfosalicylate + NADH + O2 = ? + NAD+ + H2O + CO2
show the reaction diagram
-
3'-phosphoadenylylsulfate + 5-sulfosalicylic acid = adenosine 3',5'-bisphosphate + 5-sulfo-2-(sulfooxy)benzoic acid
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
2.5 mM, 35% inhibition
-
strong
-
inactivates DDAH
-
competitive inhibition of isozyme carbonic anhydrase I and noncompetitive inhibition of isozyme carbonic anhydrase II
-

Enzyme Kinetic Parameters

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for 5-sulfosalicylic acid

ChEBI
PubChem
ChEBI
PubChem