Ligand 2-hydroxymethylglutarate

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Basic Ligand Information

Molecular Structure
Picture of 2-hydroxymethylglutarate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H10O5
2-hydroxymethylglutarate
XPQIPNORJZZYPV-UHFFFAOYSA-L
Synonyms:
(S)-2-hydroxymethylglutarate, 2-(hydroxymethyl)pentanedioate
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-formylglutarate + NADH + H+ = 2-hydroxymethylglutarate + NAD+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-hydroxymethylglutarate + NAD+ = 2-formylglutarate + NADH + H+
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-formylglutarate + NADH + H+ = 2-hydroxymethylglutarate + NAD+
show the reaction diagram
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Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.1
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References & Links

Links to other databases for 2-hydroxymethylglutarate

ChEBI
PubChem
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PubChem