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Ligand 1-oleoyl-sn-glycero-3-phosphocholine

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

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Show Natural Substrate (5 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.23

alpha-linolenoyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine = CoA + 1-oleoyl-2-alpha-linolenoyl-sn-glycero-3-phosphocholine

758095

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2.3.1.23

linoleoyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine = CoA + 1-oleoyl-2-linoleoyl-sn-glycero-3-phosphocholine

758095

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2.3.1.23

oleoyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine = CoA + 1,2-dioleoyl-lysophosphatidylcholine

758095

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2.3.1.23

oleoyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine = CoA + 1,2-dioleoyl-sn-glycero-3-phosphocholine

758095

-

2.3.1.23

4 entries

3.1.1.4

1-oleoyl-sn-glycero-3-phosphocholine + H2O = ?

691333

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Substrate in Enzyme-catalyzed Reactions (8 results)

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Show Substrate (8 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.23

acyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine = CoA + 1-oleoyl-2-acyl-sn-glycero-3-phosphocholine

486651, 486653

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2.3.1.23

alpha-linolenoyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine = CoA + 1-oleoyl-2-alpha-linolenoyl-sn-glycero-3-phosphocholine

758095

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2.3.1.23

linoleoyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine = CoA + 1-oleoyl-2-linoleoyl-sn-glycero-3-phosphocholine

758095

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2.3.1.23

oleoyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine = CoA + 1,2-dioleoyl-lysophosphatidylcholine

758095

-

2.3.1.23

oleoyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine = CoA + 1,2-dioleoyl-sn-glycero-3-phosphocholine

486657, 758095, 737051

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2.3.1.23

5 entries

2.3.1.B36

1-oleoyl-sn-glycero-3-phosphocholine + glycerophosphocholine = glycero-3-phosphocholine + 1-oleoyl-sn-glycero-3-phosphocholine

757164

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3.1.1.4

1-oleoyl-sn-glycero-3-phosphocholine + H2O = ?

691333

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3.1.1.5

1-oleoyl-sn-glycero-3-phosphocholine + H2O = oleic acid + glycerophosphorylcholine

94392, 94389, 94396, 94397

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Product in Enzyme-catalyzed Reactions (11 results)

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Show Product (11 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.43

dioleoyl-phosphatidyl choline + cholesterol = 1-oleoyl-phosphatidyl choline + cholesteryl oleate

-

-

2.3.1.B36

1-oleoyl-sn-glycero-3-phosphatidic acid + glycerophosphocholine = glycero-3-phosphatidic acid + 1-oleoyl-sn-glycero-3-phosphocholine

-

-

2.3.1.B36

1-oleoyl-sn-glycero-3-phosphocholine + glycerophosphocholine = glycero-3-phosphocholine + 1-oleoyl-sn-glycero-3-phosphocholine

-

-

2.3.1.B36

1-oleoyl-sn-glycero-3-phosphoethanolamine + glycerophosphocholine = glycero-3-phosphoethanolamine + 1-oleoyl-sn-glycero-3-phosphocholine

-

-

2.3.1.B36

1-oleoyl-sn-glycero-3-phosphoserine + glycerophosphocholine = glycero-3-phosphoserine + 1-oleoyl-sn-glycero-3-phosphocholine

-

-

2.3.1.B36

oleoyl-CoA + glycerophosphocholine = CoA + 1-oleoyl-sn-glycero-3-phosphocholine

-

-

3.1.1.4

1-oleoyl-2-palmitoyl-phosphatidylcholine + H2O = 1-oleoyl-phosphatidylcholine + palmitic acid

133918

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3.1.1.4

1,2-dioleoyl-sn-glycero-3-phosphocholine + H2O = 1-oleoyl-sn-glycero-3-phosphocholine + oleate

-

-

3.1.1.4

1,2-dioleoyl-sn-glycero-3-phosphocholine + H2O = 1-oleoyl-sn-glycero-3-phosphocholine + oleic acid

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-

3.1.1.4

1-oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine + H2O = 1-oleoyl-sn-glycero-3-phosphocholine + palmitate

-

-

3.1.1.4

1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine + H2O = 1-oleoyl-sn-glycero-3-phosphocholine + stearate

-

-

2.3.1.B36

5 entries

3.1.1.4

5 entries

Enzyme Kinetic Parameters

References & Links

Literature References (12)

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Show Reference (12 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

94389

8631810

Purification, cDNA cloning, and regulation of lysophospholipase from rat liver

1996

Sugimoto, H.; Hayashi, H.; Yamashita, S.

J. Biol. Chem.

271

7705-7711

94392

10064901

Sequence, expression in Escherichia coli, and characterizatiom of lysophospholipase II

1999

Toyoda, T.; Sugimoto, H.; Yamashita, S.

Biochim. Biophys. Acta

1437

182-193

94396

8119970

Purification, characterization, and inhibition by phosphatidic acid of lysophospholipase transacylase from rat liver

1994

Sugimoto, H.; Yamashita, S.

J. Biol. Chem.

269

6252-6258

94397

7772041

Purification and properties of lysophospholipase isoenzymes from pig gastric mucosa

1995

Sunaga, H.; Sugimoto, H.; Nagamachi, Y.; Yamashita, S.

Biochem. J.

308

551-557

133918

922032

Characterization of phospholipase A from pulmonary secretions of patients with alveolar proteinosis

1977

Sahu, S.; Lynn, W.S.

Biochim. Biophys. Acta

489

307-317

486651

9930410

Lysophosphatidylcholine acyltransferase activity in Saccharomyces cerevisiae: regulation by a high-affinity Zn2+ binding site

1998

Richard, M.G.; McMaster, C.R.

Lipids

33

1229-1234

486653

9514659

Substrate specificity of acyl-CoA:lysophospholipid acyltransferase (LAT) from pig spleen

1998

Kerkhoff, C.; Habben, K.; Gehring, L.; Resch, K.; Kaever, V.

Arch. Biochem. Biophys.

351

220-226

486657

11960748

Inhibition of the plastidial phosphatidylcholine synthesis by silver, copper, lead and mercury induced by formation of mercaptides with the lyso-PC acyltransferase

2002

Akermoun, M.; Testet, E.; Cassagne, C.; Bessoule, J.J.

Biochim. Biophys. Acta

1581

21-28

691333

18234820

Activation of phospholipase A2 by ternary model membranes

2008

Simonsen, A.C.

Biophys. J.

94

3966-3975

737051

25298156

Novel reactions in acyl editing of phosphatidylcholine by lysophosphatidylcholine transacylase (LPCT) and acyl-CoA:glycerophosphocholine acyltransferase (GPCAT) activities in microsomal preparations of plant tissues

2015

Lager, I.; Glab, B.; Eriksson, L.; Chen, G.; Banas, A.; Stymne, S.

Planta

241

347-358

757164

27758859

Cloning of glycerophosphocholine acyltransferase (GPCAT) from fungi and plants a novel enzyme phosphatidylcholine synthesis

2016

Glab, B.; Beganovic, M.; Anaokar, S.; Hao, M.S.; Rasmusson, A.G.; Patton-Vogt, J.; Banas, A.; Stymne, S.; Lager, I.

J. Biol. Chem.

291

25066-25076

758095

31407031

Acyl-CoA lysophosphatidylcholine acyltransferases (LPCATs) of Camelina sativa seeds biochemical properties and function

2019

Klinska, S.; Jasieniecka-Gazarkiewicz, K.; Banas, A.

Planta

250

1655-1670

Links to other databases for 1-oleoyl-sn-glycero-3-phosphocholine

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Show Links (1 entry)

ChEBI

PubChem

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