Ligand dioleoyl-phosphatidylcholine

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Basic Ligand Information

Molecular Structure
Picture of dioleoyl-phosphatidylcholine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C44H84NO8P
dioleoyl-phosphatidylcholine
SNKAWJBJQDLSFF-NVKMUCNASA-O
Synonyms:
1,2-dioleoyl-L-alpha-phosphatidylcholine, 1,2-dioleoyl-sn-glycero-3-phosphocholine, 1,2-dioleoyl-sn-glycerophosphocholine, 1,2-dioleoyl-sn-phosphatidylcholine, 1,2-dioleoylphosphatidylcholine, di-oleoyl phosphatidylcholine, dioleoyl-phosphatidyl choline, dioleoylphosphatidylcholine, dioleoyl phosphatidylcholine, sn-1,2-dioleoylphosphatidylcholine
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,2-dioleoyl-sn-glycero-3-phosphocholine + H2O = 1-oleoylglycerophosphocholine + oleic acid
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
oleoyl-CoA + 1-oleoyl-sn-glycero-3-phosphocholine = CoA + 1,2-dioleoyl-sn-glycero-3-phosphocholine
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (45 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,2-dioleoylphosphatidylcholine + 2 ferrocytochrome b5 + O2 + 2 H+ = 1,2-linoleoylphosphatidylcholine + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
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dioleoylphosphatidylcholine + all-trans-retinol = all-trans-retinyl oleate + 2-oleoylglycerophosphocholine
show the reaction diagram
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dioleoyl-phosphatidyl choline + cholesterol = 1-oleoyl-phosphatidyl choline + cholesteryl oleate
show the reaction diagram
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1,2-dioleoylphosphatidylcholine + H2O = oleic acid + 2-oleoylglycerophosphocholine
show the reaction diagram
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1,2-dioleoyl-sn-glycero-3-phosphocholine + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
oleoyl-CoA + 1-oleoyl-2-lysophosphatidylcholine = CoA + 1,2-dioleoyl-sn-glycero-3-phosphocholine
show the reaction diagram
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CDP-choline + 1,2-dioleoyl-sn-glycerol = CMP + 1,2-dioleoyl-sn-glycero-3-phosphocholine
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
incorporation in membrane elevates acyltransferase activity
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activation
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or other exogenous phospholipid, required for activity
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activation
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half-maximal activation at 10.4 mol%
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stimulates
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0.1 mM, 1.3fold stimulation
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3D Structure of Enzyme-Ligand-Complex (PDB) (266 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for dioleoyl-phosphatidylcholine

ChEBI
PubChem
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PubChem