Ligand 2-fluoroadenine arabinoside 5'-monophosphate

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of 2-fluoroadenine arabinoside 5'-monophosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H13FN5O7P
2-fluoroadenine arabinoside 5'-monophosphate
GIUYCYHIANZCFB-FJFJXFQQSA-N
Synonyms:
2-fluoro-9-beta-D-arabinofuranosyladenine 5'-phosphate, 2-fluoro-9-[beta-D-arabinofuranosyl]-AMP, 2-fluoro-arabinosyl-adenine 5'-monophosphate, 2-fluoro Ara-A 5'-phosphate, 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-phosphate, 9-beta-D-arabinosyl-2-fluoroadenine 5'-phosphate, 9-beta-D-arabinosyl-2-fluoroadenine monophosphate, 9-beta-D-arabinosyl 2-fluoroadenine 5'-phosphate, arabinosyl-2-fluoroadenine 5'-monophosphate, fludarabine 5'-phosphate, fludarabine monophosphate, fludarabine phosphate

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
9-beta-D-arabinosyl-2-fluoroadenine monophosphate + H2O = 9-beta-D-arabinosyl-2-fluoroadenine + phosphate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + 2-fluoro-arabinosyl-adenine = ADP + 2-fluoro-arabinosyl-adenine 5'-monophosphate
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
10
-
pH 8.3, 25°C

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0002
-
IC50-value in cell culture 0.0002 mM

References & Links

Links to other databases for 2-fluoroadenine arabinoside 5'-monophosphate

ChEBI
PubChem
-
PubChem