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Kinetic and catalytic mechanisms of protein kinases
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Aminopeptidase Y, a new aminopeptidase from Saccharomyces cerevisiae. Purification, properties, localization, and processing by protease B
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The effect of cAMP and cGMP on the activity and substrate specificity of protein kinase A from methylotrophic yeast Pichia pastoris
2003
Frajnt, M.; Cytrynska, M.; Jakubowicz, T.
Acta Biochim. Pol.
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Characterization of a type I regulatory subunit of cAMP-dependent protein kinase from the bivalve mollusk Mytilus galloprovincialis
2003
Diaz-Enrich, M.J.; Ibarguren, I.; Hellman, U.; Villamarin, J.A.
Arch. Biochem. Biophys.
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Isoforms of cAMP-dependent protein kinase in the bivalve mollusk Mytilus galloprovincialis: activation by cyclic nucleotides and effect of temperature
2004
Bardales, J.R.; Diaz-Enrich, M.J.; Ibarguren, I.; Villamarin, J.A.
Arch. Biochem. Biophys.
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Differential effects of substrate on type I and type II PKA holoenzyme dissociation
2004
Vigil, D.; Blumenthal, D.K.; Brown, S.; Taylor, S.S.; Trewhella, J.
Biochemistry
43
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Kinetic analysis of inhibition of cAMP-dependent protein kinase catalytic subunit by the peptide-nucleoside conjugate AdcAhxArg6
2004
Kuznetsov, A.; Uri, A.; Raidaru, G.; Jarv, J.
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Phosphorylation of NF-kappaB proteins by cyclic GMP-dependent kinase. A noncanonical pathway to NF-kappaB activation
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Folding and activity of cAMP-dependent protein kinase mutants
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Langer, T.; Sreeramulu, S.; Vogtherr, M.; Elshorst, B.; Betz, M.; Schieborr, U.; Saxena, K.; Schwalbe, H.
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cAMP-dependent protein kinase of Manduca sexta phosphorylates but does not activate the fat body triglyceride lipase
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Patel, R.; Soulages, J.L.; Wells, M.A.; Arrese, E.L.
Insect Biochem. Mol. Biol.
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Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain
2004
Liu, S.J.; Zhang, J.Y.; Li, H.L.; Fang, Z.Y.; Wang, Q.; Deng, H.M.; Gong, C.X.; Grundke-Iqbal, I.; Iqbal, K.; Wang, J.Z.
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Substrate enhances the sensitivity of type I protein kinase a to cAMP
2005
Viste, K.; Kopperud, R.K.; Christensen, A.E.; Doskeland, S.O.
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Regulation of the G2/M transition in Xenopus oocytes by the cAMP-dependent protein kinase
2005
Eyers, P.A.; Liu, J.; Hayashi, N.R.; Lewellyn, A.L.; Gautier, J.; Maller, J.L.
J. Biol. Chem.
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Consequences of lysine 72 mutation on the phosphorylation and activation state of cAMP-dependent kinase
2005
Iyer, G.H.; Moore, M.J.; Taylor, S.S.
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Crystal structure of a cAMP-dependent protein kinase mutant at 1.26A: new insights into the catalytic mechanism
2004
Yang, J.; Ten Eyck, L.F.; Xuong, N.H.; Taylor, S.S.
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A transitory activation of protein kinase-A induces a sustained tau hyperphosphorylation at multiple sites in N2a cells-imply a new mechanism in Alzheimer pathology
2006
Zhang, Y.; Li, H.L.; Wang, D.L.; Liu, S.J.; Wang, J.Z.
J. Neural Transm.
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Characterization of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG): Antiparasitic activity of a PKG inhibitor
2006
Diaz, C.A.; Allocco, J.; Powles, M.A.; Yeung, L.; Donald, R.G.; Anderson, J.W.; Liberator, P.A.
Mol. Biochem. Parasitol.
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Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase
2004
Tian, L.; Coghill, L.S.; McClafferty, H.; MacDonald, S.H.; Antoni, F.A.; Ruth, P.; Knaus, H.G.; Shipston, M.J.
Proc. Natl. Acad. Sci. USA
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Characterization of the cAMP-dependent protein kinase catalytic subunit Cgamma expressed and purified from sf9 cells
2004
Zhang, W.; Morris, G.Z.; Beebe, S.J.
Protein Expr. Purif.
35
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A simple electrostatic switch important in the activation of type I protein kinase A by cyclic AMP
2006
Vigil, D.; Lin, J.H.; Sotriffer, C.A.; Pennypacker, J.K.; McCammon, J.A.; Taylor, S.S.
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Biochemical characterization of Ca2+/calmodulin dependent protein kinase from Candida albicans
2003
Dhillon, N.K.; Sharma, S.; Khuller, G.K.
Mol. Cell. Biochem.
252
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Catalytic subunit of cAMP-dependent protein kinase from a catch muscle of the bivalve mollusk Mytilus galloprovincialis: purification, characterization, and phosphorylation of muscle proteins
2006
Bejar, P.; Villamarin, J.A.
Arch. Biochem. Biophys.
450
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E230Q mutation of the catalytic subunit of cAMP-dependent protein kinase affects local structure and the binding of peptide inhibitor
2006
Ung, M.; Lu, B.; McCammon, J.A.
Biopolymers
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Identification of ChChd3 as a novel substrate of the cAMP-dependent protein kinase (PKA) using an analog-sensitive catalytic subunit
2007
Schauble, S.; King, C.C.; Darshi, M.; Koller, A.; Shah, K.; Taylor, S.S.
J. Biol. Chem.
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Redox regulation of cAMP-dependent protein kinase signaling: kinase versus phosphatase inactivation
2007
Humphries, K.M.; Pennypacker, J.K.; Taylor, S.S.
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Protein kinase A regulates growth, sporulation, and pigment formation in Aspergillus fumigatus
2008
Grosse, C.; Heinekamp, T.; Kniemeyer, O.; Gehrke, A.; Brakhage, A.A.
Appl. Environ. Microbiol.
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Inactive forms of the catalytic subunit of protein kinase A are expressed in the brain of higher primates
2008
Larsen, A.C.; Kvissel, A.K.; Hafte, T.T.; Avellan, C.I.; Eikvar, S.; Rootwelt, T.; Orstavik, S.; Skalhegg, B.S.
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Identification of multiple isoforms of the cAMP-dependent protein kinase catalytic subunit in the bivalve mollusc Mytilus galloprovincialis
2008
Bardales, J.R.; Hellman, U.; Villamarin, J.A.
FEBS J.
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E-cadherin expression in postnatal Schwann cells is regulated by the cAMP-dependent protein kinase A pathway
2008
Crawford, A.T.; Desai, D.; Gokina, P.; Basak, S.; Kim, H.A.
Glia
56
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Signaling the signal, cyclic AMP-dependent protein kinase inhibition by insulin-formed H2O2 and reactivation by thioredoxin
2008
de Pina, M.Z.; Vazquez-Meza, H.; Pardo, J.P.; Rendon, J.L.; Villalobos-Molina, R.; Riveros-Rosas, H.; Pina, E.
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Protein kinase A-dependent step(s) in hepatitis C virus entry and infectivity
2008
Farquhar, M.J.; Harris, H.J.; Diskar, M.; Jones, S.; Mee, C.J.; Nielsen, S.U.; Brimacombe, C.L.; Molina, S.; Toms, G.L.; Maurel, P.; Howl, J.; Herberg, F.W.; van Ijzendoorn, S.C.; Balfe, P.; McKeating, J.A.
J. Virol.
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Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes
2008
Petersen, R.K.; Madsen, L.; Pedersen, L.M.; Hallenborg, P.; Hagland, H.; Viste, K.; Doskeland, S.O.; Kristiansen, K.
Mol. Cell. Biol.
28
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cAMP promotes neurite outgrowth and extension through protein kinase A but independently of Erk activation in cultured rat motoneurons
2008
Aglah, C.; Gordon, T.; Posse de Chaves, E.I.
Neuropharmacology
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Adrenergic regulation of cAMP/protein kinase A pathway in corneal epithelium and endothelium
2008
Grueb, M.; Bartz-Schmidt, K.U.; Rohrbach, J.M.
Ophthalmic Res.
40
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Dual regulation of the ATP-sensitive potassium channel by activation of cGMP-dependent protein kinase
2008
Chai, Y.; Lin, Y.F.
Pflugers Arch.
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Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase
2008
McRobert, L.; Taylor, C.J.; Deng, W.; Fivelman, Q.L.; Cummings, R.M.; Polley, S.D.; Billker, O.; Baker, D.A.
PLoS Biol.
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Allosteric communication between cAMP binding sites in the RI subunit of protein kinase A revealed by NMR
2010
Byeon, I.J.; Dao, K.K.; Jung, J.; Keen, J.; Leiros, I.; Doskeland, S.O.; Martinez, A.; Gronenborn, A.M.
J. Biol. Chem.
285
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Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase
2012
Bastidas, A.C.; Deal, M.S.; Steichen, J.M.; Keshwani, M.M.; Guo, Y.; Taylor, S.S.
J. Mol. Biol.
422
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Biochemical characterization of the cAMP-dependent protein kinase regulatory subunit-like protein from Trypanosoma equiperdum, detection of its inhibitory activity, and identification of potential interacting proteins
2020
Araujo, N.A.; Rincon, M.; Vonasek, E.; Calabokis, M.; Bubis, J.
Biochimie
168
110-123
Crystal structure of cGMP-dependent protein kinase Ib cyclic nucleotide-binding-B domain Rp-cGMPS complex reveals an apo-like, inactive conformation
2017
Campbell, J.C.; VanSchouwen, B.; Lorenz, R.; Sankaran, B.; Herberg, F.W.; Melacini, G.; Kim, C.
FEBS Lett.
591
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Kinetics and inhibition studies of the L205R mutant of cAMP-dependent protein kinase involved in Cushings syndrome
2018
Luzi, N.M.; Lyons, C.E.; Peterson, D.L.; Ellis, K.C.
FEBS open bio
8
606-613
A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP
2020
Chan, M.H.; Aminzai, S.; Hu, T.; Taran, A.; Li, S.; Kim, C.; Pilz, R.B.; Casteel, D.E.
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295
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