Ligand sym-homospermidine

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Basic Ligand Information

Molecular Structure
Picture of sym-homospermidine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H21N3
sym-homospermidine
UODZHRGDSPLRMD-UHFFFAOYSA-N
Synonyms:
1,9-Diamino-5-azanonane, bis-(4-aminobutyl)amine, Homospermidine, N-(4-aminobutyl)-1,4-butanediamine, N-(4-aminobutyl)butane-1,4-diamine, N-(delta-aminobutyl)tetramethylenediamine

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl 3-(methylthio)propylamine + homospermidine = S-methyl-5'-thioadenosine + ?
show the reaction diagram
-
S-adenosylmethioninamine + sym-homospermidine = 5'-methylthioadenosine + ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (21 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
95% inhibition at 0.01 mM, 92% inhibition at 0.1 mM and 30% inhibition at 1 mM
-
weak
-
competitive
-
inhibition of deoxyhypusine synthesis
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.95
-
-

References & Links

Links to other databases for sym-homospermidine

ChEBI
PubChem
ChEBI
PubChem