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Ligand streptidine 6-phosphate Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information
C8 H1 9 N6 O7 P
streptidine 6-phosphate
UUUGVWGQJIFFRM-XJQRDMAOSA-N
O-phosphorylstreptidine, streptidine phosphate
Related pathways
MetaCyc
streptomycin biosynthesis
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
dTDP-L-dihydrostreptose + streptidine 6-phosphate = ?
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Substrate in Enzyme-catalyzed Reactions (5 results)
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streptidine 6-phosphate + scyllo-inosaminephosphate = ?
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streptidine phosphate + glycylglycine = ?
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dTDP-L-dihydrostreptose + streptidine 6-phosphate = ?
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dTDP-L-dihydrostreptose + streptidine 6-phosphate = dTDP + O-alpha-L-dihydrostreptosyl-1,4-streptidine 6-phosphate
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streptidine 6-phosphate + H2O = dihydrostreptomycin + phosphate
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Product in Enzyme-catalyzed Reactions (1 result)
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streptidine + ATP = streptidine 6-phosphate + ADP
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Enzyme Kinetic Parameters
References & Links Literature References (8)
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Streptomycin-6-P phosphohydrolase
1975
Walker, J.B.
Methods Enzymol.
43
465-470
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Amidinotranferases
1973
Walker, J.B.
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
9
497-509
Enzymic studies on the biosynthesis of streptomycin
1966
Walker, M.S.; Walker, J.B.
J. Biol. Chem.
241
1262-1270
L-Arginine:inosamine-P amindinotransferase (s)
1975
Walker, J.B.
Methods Enzymol.
43
451-458
Crystal Structure of L-Arginine:Inosamine-Phosphate Amidinotransferase StrB1 from Streptomyces griseus: An Enzyme Involved in Streptomycin Biosynthesis
1998
Fritsche, E.; Bergner, A.; Humm, A.; Piepersberg, W.; Huber, R.
Biochemistry
37
17664-17672
Biosynthesis of streptomycin. Purification and properties of a dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase from Streptomyces griseus
1980
Kniep, B.; Grisebach, H.
Eur. J. Biochem.
105
139-144
Streptomycin biosynthesis. Enzymatic synthesis of O-phosphorylstreptidine from streptidine and adenosinetriphosphate
1967
Walker, J.B.; Walker, M.S.
Biochim. Biophys. Acta
148
335-341
ATP:streptomycin 6-phosphotransferase
1975
Walker, J.B.
Methods Enzymol.
43
628-632
Links to other databases for streptidine 6-phosphate
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