Ligand 1-deoxy-D-xylulose 5-phosphate

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Basic Ligand Information

Molecular Structure
Picture of 1-deoxy-D-xylulose 5-phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H11O7P
1-deoxy-D-xylulose 5-phosphate
AJPADPZSRRUGHI-RFZPGFLSSA-N
Synonyms:
1-deoxy-D-xylulose-5-phosphate, 3-[2H]-D-1-deoxyxylulose-5-phosphate, 4-[2H]-D-1-deoxyxylulose-5-phosphate


Show all pahtways known for Show all BRENDA pathways known for 1-deoxy-D-xylulose 5-phosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-deoxy-D-xylulose 5-phosphate + NADPH + H+ = 2-C-methyl-D-erythritol 4-phosphate + NADP+
show the reaction diagram
1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O
show the reaction diagram

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2
show the reaction diagram
-
-
ATP + 1-deoxy-D-xylulose = ADP + 1-deoxy-D-xylulose 5-phosphate
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O
show the reaction diagram

Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
methyl-D-erythritol-4-phosphate + NADP+ = 1-deoxy-D-xylulose-5-phosphate + NADPH
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
substrate inhibition

3D Structure of Enzyme-Ligand-Complex (PDB) (6 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (21 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (41 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.1
-
pH 7.9, 30°C, recombinant His-tagged enzyme

References & Links

Links to other databases for 1-deoxy-D-xylulose 5-phosphate

ChEBI
PubChem
ChEBI
PubChem