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Ligand L-Albizziin

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

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Show Substrate (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.4.3.2

L-albizziin + H2O + O2 = alpha-keto-beta-ureidopropionic acid + NH3 + H2O2

391804

-

2.6.1.15

L-albizziin + glyoxylate = glycine + 2-imidazolidone-5-hydroxy-5-carboxylic acid

639899, 391804

-

3.5.1.2

L-albizziin + H2O = ? + NH3

754315

-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

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Show Inhibitors (4 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.4.1.14

-

391460

-

1.4.1.14

less inhibitory than L-homocysteine sulfonamide, methionine sulfone and ethionine sulfone

391475

-

1.4.1.14

2 entries

4.3.1.13

20 mM, 20% inhibition

6042

-

6.3.5.4

-

1705, 1709, 1713

-

Enzyme Kinetic Parameters

K_i Value (1 result)

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Show KI Value (1 entry)

EC NUMBER

KI VALUE [MM]

KI VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

1.4.1.14

0.1

-

-

391475

References & Links

Literature References (9)

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Show Reference (9 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

1705

-

Kinetic studies on asparagine synthetase from mung beans (Vigna radiata (L) Wilczek) with a phosphonate analogue of the proposed reaction intermediate

1982

Pike, D.C.; Beevers, L.

Biochim. Biophys. Acta

708

203-209

1709

-

The purification and properties of glutamine-dependent asparagine synthetase isolated from Lupinus luteus

1975

Lea, P.J.; Fowden, L.

Proc. R. Soc. Lond. B Biol. Sci.

192

13-26

1713

5076775

Glutamine-dependent asparagine synthetase from leukemia cells. Chloride dependence mechanism of action and inhibition

1972

Horowitz, B.; Meister, A.

J. Biol. Chem.

247

6708-6719

6042

4761084

Enzymatic conversion of O-carbamyl-L-serine to pyruvate and ammonia

1973

Cooper, A.J.L.; Meister, A.

Biochem. Biophys. Res. Commun.

55

780-787

391460

3911003

Glutamate synthase from Escherichia coli, Klebsiella aerogenes, and Saccharomyces cerevisiae

1985

Meister, A.

Methods Enzymol.

113

327-337

391475

7047525

Inhibition by homocysteine sulfonamide of glutamate synthase purified from Saccharomyces cerevisiae

1982

Masters, D.S.; Meister, A.

J. Biol. Chem.

257

8711-8715

391804

4797019

Action of liver glutamine transaminase and L-amino acid oxidase on several glutamine analogs. Preparation and properties of the 4-S, O, and NH analogs of alpha-ketoglutaramic acid

1973

Cooper, A.J.L.; Meister, A.

J. Biol. Chem.

248

8499-8505

639899

4762917

Activity of liver glutamine transaminase toward L-gamma-glutamyl hydrazones of alpha-keto acids

1973

Cooper, A.J.L.; Meister, A.

J. Biol. Chem.

248

8489-8498

754315

31130583

Purification, characterization and anticancer efficiency of L-glutaminase from Aspergillus flavus

2019

Abu-Tahon, M.A.; Isaac, G.S.

J. Gen. Appl. Microbiol.

65

284-292

Links to other databases for L-Albizziin

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Show Links (1 entry)

ChEBI

PubChem