Ligand (S)-methyl 4-tolyl sulfoxide
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Basic Ligand Information
Molecular Structure

C8H10OS
(S)-methyl 4-tolyl sulfoxide
FEVALTJSQBFLEU-JTQLQIEISA-N
(S)-methyl p-tolyl sulfoxide, 1-methyl-4-[(S)-methylsulfinyl]benzene, methyl 4-methylphenyl (S)-sulfoxide, S-methyl p-tolyl sulfoxide
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (4 results)
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(S)-methyl 4-tolyl sulfoxide + thioredoxin = ?
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S-methyl p-tolyl sulfoxide + thioredoxin A = 1-methyl-4-(methylsulfanyl)benzene + thioredoxin A disulfide + H2O
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S-methyl p-tolyl sulfoxide + thioredoxin C = 1-methyl-4-(methylsulfanyl)benzene + thioredoxin C disulfide + H2O
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(S)-methyl p-tolyl sulfoxide + reduced methyl viologen + H2O = methyl p-tolyl sulfide + oxidized methyl viologen
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Product in Enzyme-catalyzed Reactions (1 result)
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4-methyl-thioanisole + NADPH + H+ + O2 = methyl 4-methylphenyl (S)-sulfoxide + NADP+ + H2O
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Enzyme Kinetic Parameters
References & Links
Literature References (3)
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Identification and characterization of a putative active site for peptide methionine sulfoxide reductase (MsrA) and its substrate stereospecificity
2000
Moskovitz, J.; Poston, J.M.; Berlett, B.S.; Nosworthy, N.J.; Szczepanowski, R.; Stadtman, E.R.
J. Biol. Chem.
275
14167-14172
Asymmetric reduction of racemic sulfoxides by dimethyl sulfoxide reductases from Rhodobacter capsulatus, Escherichia coli and Proteus species
1998
Hanlon, S.; Graham, D.; Hogan, P.; Holt, R.; Reeve, C.; Shaw, A.; McEwan, A.
Microbiology
144
2247-2253
Salmonella Typhimurium methionine sulfoxide reductase A (MsrA) prefers TrxA in repairing methionine sulfoxide
2017
Dixit, S.K.; Hota, D.P.; Rajan, P.; Mishra, P.K.; Goswami, T.K.; Mahawar, M.
Prep. Biochem. Biotechnol.
47
137-142
Links to other databases for (S)-methyl 4-tolyl sulfoxide