Ligand 5-fluorocytosine

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of 5-fluorocytosine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H4FN3O
5-fluorocytosine
XRECTZIEBJDKEO-UHFFFAOYSA-N
Synonyms:
5-fluoro-cytosine

Show all pahtways known for Show all pathways known for 5-fluorocytosine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-fluorocytosine + H2O = 5-fluorouracil + NH3
show the reaction diagram

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2'-deoxyuridine + 5-fluorocytosine = 2'-deoxy-5-fluorocytidine + uracil
show the reaction diagram
-
5-fluorocytosine + H2O = 5-fluorouracil + NH3
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-fluorocytosine-mismatched double-stranded DNA + H2O = 5-fluorocytosine + double-stranded DNA with abasic site
show the reaction diagram
-
-
5-fluorocytidine + H2O = D-ribose + 5-fluorocytosine
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (23 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (29 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.42
-
-

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.657
-
-

References & Links

Links to other databases for 5-fluorocytosine

ChEBI
PubChem
ChEBI
PubChem