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Ligand DL-cysteine

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.5.1.59

geranylgeranyl diphosphate + Rac-cysteine = S-geranylgeranyl-Rac + diphosphate

738097, 738895

-

Substrate in Enzyme-catalyzed Reactions (4 results)

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Show Substrate (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.1.1.10

S-adenosyl-L-methionine + DL-cysteine = S-adenosyl-L-homocysteine + S-methyl-DL-cysteine

676384

-

2.1.1.280

S-adenosyl-L-methionine + DL-cysteine = ?

723454

-

2.5.1.59

geranylgeranyl diphosphate + Rac-cysteine = S-geranylgeranyl-Rac + diphosphate

738097, 738895

-

4.3.1.10

DL-cysteine = ?

6035

-

Product in Enzyme-catalyzed Reactions (3 results)

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Show Product (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.5.1.144

O-acetyl-L-serine + sulfide = 2-amino-3-sulfanylpropanoic acid + acetate

0

-

3.5.1.87

N-carbamoyl-DL-cysteine + H2O = DL-cysteine + CO2 + NH3

0

-

7.6.2.14

ATP + H2O + cysteine-[cysteine-binding protein][side 1] = ADP + phosphate + cysteine[side 2] + [cysteine-binding protein][side 1]

0

-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

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Show Inhibitors (2 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

2.6.1.19

-

637056

-

3.5.5.1

97% residual activity at 1% (w/v)

684594

-

Enzyme Kinetic Parameters

References & Links

Literature References (7)

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Show Reference (7 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

6035

1260040

Substrate specificity of the L-serine O-sulphate degrading activities of Pseudomonas FR

1976

Tudball, N.; O'Neill, J.G.

Biochim. Biophys. Acta

429

616-623

637056

7362249

gamma-Aminobutyrate:alpha-ketoglutarate aminotransferase from Pseudomonas sp. F-126: purification, crystallization, and enzymologic properties

1980

Yonaha, K.; Toyama, S.

Arch. Biochem. Biophys.

200

156-164

676384

17391716

Biochemical and molecular characterization of the homocysteine S-methyltransferase from broccoli (Brassica oleracea var. italica)

2007

Lyi, S.M.; Zhou, X.; Kochian, L.V.; Li, L.

Phytochemistry

68

1112-1119

684594

17061133

Purification and characterization of a nitrilase from Aspergillus niger K10

2006

Kaplan, O.; Vejvoda, V.; Plihal, O.; Pompach, P.; Kavan, D.; Bojarova, P.; Bezouska, K.; Mackova, M.; Cantarella, M.; Jirku, V.; Kren, V.; Martinkova, L.

Appl. Microbiol. Biotechnol.

73

567-575

723454

15863700

Molecular and biochemical characterization of the selenocysteine Se-methyltransferase gene and Se-methylselenocysteine synthesis in broccoli

2005

Lyi, S.M.; Heller, L.I.; Rutzke, M.; Welch, R.M.; Kochian, L.V.; Li, L.

Plant Physiol.

138

409-420

738097

25450772

Farnesyltransferase and geranylgeranyltransferase I: structures, mechanism, inhibitors and molecular modeling

2015

Shen, M.; Pan, P.; Li, Y.; Li, D.; Yu, H.; Hou, T.

Drug Discov. Today

20

267-276

738895

23534605

Geranylgeranyltransferase I mediates BDNF-induced synaptogenesis

2013

Li, Z.; Sun, C.; Zhang, T.; Mo, J.; Shi, Q.; Zhang, X.; Yuan, M.; Chen, L.; Mao, X.; Yu, R.; Zhou, X.

J. Neurochem.

125

698-712

Links to other databases for DL-cysteine

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Show Links (1 entry)

ChEBI

PubChem