Ligand Benzoyl-Ala

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Basic Ligand Information

Molecular Structure
Picture of Benzoyl-Ala (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H11NO3
Benzoyl-Ala
HDARBOBPRWGUCO-IMJABKPDSA-N
Synonyms:
benzoyl-L-Ala, Benzoyl-L-alanine, benzoylalanine, L-Bz-Ala, N-alpha-Benzoyl-L-Ala, N-Benzoyl-Ala, N-benzoyl-L-alanine, N-benzoylalanine, Nalpha-Benzoyl-Ala, Nalpha-benzoyl-L-Ala

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzoyl-Ala + H2O = benzoate + Ala
show the reaction diagram
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L-Bz-Ala + H2O = benzoic acid + L-alanine
show the reaction diagram
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N-Benzoyl-Ala + H2O = Benzoate + Ala
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
benzoyl-CoA + L-alanine = CoA + N-benzoyl-L-alanine
show the reaction diagram
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benzoyl-CoA + alanine = CoA + N-benzoylalanine
show the reaction diagram
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benzoyl-Ala-Arg + H2O = benzoyl-Ala + Arg
show the reaction diagram
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benzoyl-L-Ala-4-guanidinophenyl ester + H2O = benzoyl-L-Ala + 4-guanidinophenol
show the reaction diagram
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Nalpha-benzoyl-L-Ala 4-nitroanilide + H2O = Nalpha-benzoyl-L-Ala + 4-nitroaniline
show the reaction diagram
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Benzoyl-L-alanine methyl ester + H2O = Benzoyl-L-alanine + methanol
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
KMO inhibitor that mimics the substrate structure, and also stimulates reduction of the flavin by NADPH
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competitive vs. benzoyl-CoA
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at least 30% inhibition at 0.3 mM; competitive, Ki: 0.009 mM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
2.8
-
at pH 6.5 and 35C

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
4.3
-
-
0.014
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at pH 6.5 and 35C

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
7.9
-
-
55.2
-
with variable Gly concentration
0.009
-
-

References & Links

Links to other databases for Benzoyl-Ala

ChEBI
PubChem
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PubChem