Ligand 2-methylpropane-1,2-diol
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Basic Ligand Information
Molecular Structure

C4H10O2
2-methylpropane-1,2-diol
BTVWZWFKMIUSGS-UHFFFAOYSA-N
2-methylpropan-1,2-diol, isobutane-1,2-diol
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)
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2-methylpropane-1,2-diol + electron acceptor = 2-hydroxy-2-methylpropanal + reduced electron acceptor
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2-methylpropane-1,2-diol + NAD+ = 2-hydroxy-2-methylpropanal + NADH + H+
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Substrate in Enzyme-catalyzed Reactions (2 results)
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2-methylpropane-1,2-diol + electron acceptor = 2-hydroxy-2-methylpropanal + reduced electron acceptor
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2-methylpropane-1,2-diol + NAD+ = 2-hydroxy-2-methylpropanal + NADH + H+
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Product in Enzyme-catalyzed Reactions (2 results)
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tert-butyl alcohol + NADPH + H+ + O2 = 2-methylpropan-1,2-diol + NADP+ + 2 H2O
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tert-butyl alcohol + NADPH + H+ + O2 = 2-methylpropane-1,2-diol + NADP+ + H2O
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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Metabolism of 2-methylpropene (isobutylene) by the aerobic bacterium Mycobacterium sp. strain ELW1
2015
Kottegoda, S.; Waligora, E.; Hyman, M.
Appl. Environ. Microbiol.
81
1966-1976
Genes involved in the methyl tert-butyl ether (MTBE) metabolic pathway of Mycobacterium austroafricanum IFP 2012
2006
Lopes Ferreira, N.; Labbe, D.; Monot, F.; Fayolle-Guichard, F.; Greer, C.W.
Microbiology
152
1361-1374
Links to other databases for 2-methylpropane-1,2-diol