Ligand Gly-Pro

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Basic Ligand Information

Molecular Structure
Picture of Gly-Pro (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C7H12N2O3
Gly-Pro
KZNQNBZMBZJQJO-YFKPBYRVSA-N
Synonyms:
Gly-L-Pro, Gly-Pro-OH, glycyl-L-proline

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Thr-Gly-Leu-Phe-Gln-Gly-Pro + H2O = Thr-Gly-Leu-Phe-Gln + Gly-Pro
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-L-glutamyl-4-nitroanilide + glycyl-L-proline = 4-nitroaniline + 5-L-glutamyl-glycyl-L-proline
show the reaction diagram
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Gly-Pro + H2O = Gly + Pro
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (75 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Pro-Gly-Pro + H2O = Pro + Gly-Pro
show the reaction diagram
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Gly-L-Pro-2-naphthylamide + H2O = Gly-L-Pro + 2-naphthylamine
show the reaction diagram
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Gly-Pro-p-nitroanilide + H2O = Gly-Pro + p-nitroaniline
show the reaction diagram
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Gly-Pro-p-nitroanilide + H2O = Gly-Pro + p-nitroaniline
show the reaction diagram
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Gly-Pro-4-methoxy-beta-naphthylamide + H2O = Gly-Pro + 4-methoxy-beta-naphthylamine
show the reaction diagram
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Dinitrophenyl-poly-(Pro-Gly-Pro) + H2O = Gly-Pro + ?
show the reaction diagram
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Gly-Pro-4-nitroanilide + H2O = Gly-Pro + 4-nitroaniline
show the reaction diagram
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Gly-Pro-4-methylcoumaryl-7-amide + H2O = Gly-Pro + 7-amino-4-methylcoumarin
show the reaction diagram
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Carboxybenzoyl-Gly-Pro-Leu-Gly-Pro-OH + H2O = Carboxybenzoyl-Gly-Pro-Leu + Gly-Pro-OH
show the reaction diagram
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Thr-Gly-Leu-Phe-Gln-Gly-Pro + H2O = Thr-Gly-Leu-Phe-Gln + Gly-Pro
show the reaction diagram
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Thr-Arg-Pro-Ile-Ile-Thr-Thr-Ala-Gly-Pro + H2O = Thr-Arg-Pro-Ile-Ile-Thr-Thr-Ala + Gly-Pro
show the reaction diagram
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carbobenzoxy-Gly-Pro-Leu-Gly-Pro + H2O = carbobenzoxy-Gly-Pro-Leu + Gly-Pro
show the reaction diagram
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glutaryl-glycyl-L-proline + H2O = glutarate + glycyl-L-proline
show the reaction diagram
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ATP + glycine + L-proline = ADP + phosphate + glycyl-L-proline
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50: 252.63 mM
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (14 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
5.3
-
versus Gly-Pro-4-nitroanilide

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
252.63
-
IC50: 252.63 mM

References & Links

Links to other databases for Gly-Pro

ChEBI
PubChem
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PubChem