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Ligand 3-methoxytyramine Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C9 H1 3 NO2
3-methoxytyramine
DIVQKHQLANKJQO-UHFFFAOYSA-N
3-methoxydopamine, 3-O-methyldopamine, 4-(2-aminoethyl)-2-methoxyphenol
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (3 results)
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feruloyl-CoA + 3-methoxytyramine = CoA + feruloyl-3-methoxytyramine
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acetyl-CoA + 3-methoxytyramine = CoA + ?
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acetyl-CoA + 3-methoxytyramine = CoA + N-acetyl-3-methoxytyramine
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Product in Enzyme-catalyzed Reactions (5 results)
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2 S-adenosyl-L-methionine + dopamine = 2 S-adenosyl-L-homocysteine + 4-O-methyldopamine + 3-O-methyldopamine
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3-hydroxytyramine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + 3-methoxytyramine
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S-adenosyl-L-methionine + dopamine = S-adenosyl-L-homocysteine + 3-methoxytyramine
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dopamine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + 3-O-methyldopamine
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S-adenosyl-L-methionine + dopamine = S-adenosyl-L-homocysteine + 3-O-methyldopamine
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Inhibitor in Enzyme-catalyzed Reactions (2 results)
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0.06 mM, 50% inhibition
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Enzyme Kinetic Parameters
KM Value (2 results)
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References & Links Literature References (5)
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Inhibition of dihydropteridine reductase by catecholamines and related compounds
1983
Shen, R.S.
Biochim. Biophys. Acta
743
129-135
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The biosynthesis of feruloyltyramine in Nicotiana tabacum
1984
Negrel, J.; Martin, C.
Phytochemistry
23
2797-2801
Purification, characterization and partial amino acid sequencing of hydroxycinnamoyl-CoA:tyramine N-(hydroxycinnamoyl)transferase from tobacco cell-suspension cultures
1997
Negrel, J.; Javelle, F.
Eur. J. Biochem.
247
1127-1135
Studies on the specificity of tyrosine-alpha-ketoglutarate transaminase
1964
Jacoby, G.A.; La Du, B.N.
J. Biol. Chem.
239
419-424
Purification of the recombinant human serotonin N-acetyltransferase (EC 2.3.1.87): further characterization of and comparison with AANAT from other species
2004
Ferry, G.; Ubeaud, C.; Dauly, C.; Mozo, J.; Guillard, S.; Berger, S.; Jimenez, S.; Scoul, C.; Leclerc, G.; Yous, S.; Delagrange, P.; Boutin, J.A.
Protein Expr. Purif.
38
84-98
Links to other databases for 3-methoxytyramine
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