Ligand cocaine

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Basic Ligand Information

Molecular Structure
Picture of cocaine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C17H21NO4
cocaine
ZPUCINDJVBIVPJ-UHFFFAOYSA-N
Synonyms:
(+/-)-cocaine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cocaine + H2O = O-benzoylecgonine + methanol
show the reaction diagram
-
cocaine + ethanol = cocaethylene + methanol
show the reaction diagram
-
cocaine + H2O = ecgonine methyl ester + benzoate
show the reaction diagram
-
cocaine + H2O = ecgonine methyl ester + benzoate
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cocaine = ?
show the reaction diagram
-
cocaine + ethanol = cocaethylene + methanol
show the reaction diagram
-
cocaine + H2O = ecgonine methyl ester + benzoate
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
cocaine treatment causes an increase in the ventral striatum in enzyme specific activity and enzyme relative mRNA amount determined by real time RT-PCR
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
10 mM, below 10% residual activity
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (32 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (38 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for cocaine

ChEBI
PubChem
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PubChem