Ligand 2-Hydroxycyclohexan-1-one
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Basic Ligand Information
Molecular Structure
C6H10O2
2-Hydroxycyclohexan-1-one
HZIRBXILQRLFIK-VPZZKNKNSA-N
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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2-Hydroxycyclohexan-1-one + NADPH + O2 = ?
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)
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trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH
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trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH + H+
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Substrate in Enzyme-catalyzed Reactions (4 results)
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2-hydroxycyclohexanone + NADH = ? + NAD+
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2-hydroxycyclohexanone + NADPH + O2 = 1-oxa-2-oxo-3-hydroxycycloheptane + NADP+ + H2O
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2-hydroxycyclohexan-1-one + NADPH + O2 = 1-oxa-2-oxo-7-hydroxycycloheptane + NADP+ + H2O
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2-Hydroxycyclohexan-1-one + NADPH + O2 = ?
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Product in Enzyme-catalyzed Reactions (3 results)
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trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH
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trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH + H+
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1,2-cyclohexanediol + ferricyanide = 2-hydroxycyclohexanone + ferrocyanide
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Enzyme Kinetic Parameters
KM Value (3 results)
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References & Links
Literature References (8)
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The metabolism of trans-cyclohexan-1,2-diol by an Acinetobacter species
1977
Davey, J.F.; Trudgill, P.W.
Eur. J. Biochem.
74
115-127
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Enzyme reactions involved in anaerobic cyclohexanol metabolism by a denitrifying Pseudomonas species
1989
Dangel, W.; Tschech, A.; Fuchs, G.
Arch. Microbiol.
152
273-279
Isolation and characterization of a cyclohexane-metabolizing Xanthobacter sp.
1985
Trower, M.K.; Buckland, R.M.; Higgins, R.; Griffin, M.
Appl. Environ. Microbiol.
49
1282-1289
Characterization of an FMN-containing cyclohexanone monooxygenase from a cyclohexane-grown Xanthobacter sp
1989
Trower, M.K.; Buckland, R.M.; Griffin, M.
Eur. J. Biochem.
181
199-206
Comparative study of the ability of three Xanthobacter species to metabolize cycloalkanes
1986
Magor, A.M.; Warburton, J.; Trower, M.K.; Griffin, M.
Appl. Environ. Microbiol.
52
665-671
The purification and properties of cyclohexanone oxygenase from Nocardia globerula CL1 and Acinetobacter NCIB 9871
1976
Donoghue, N.A.; Norris, D.B.; Trudgill, P.W.
Eur. J. Biochem.
63
175-192
Multiple forms of cyclohexanone oxygenase from Nocardia globerula CL1
1976
Norris, D.B.; Trudgill, P.W.
Eur. J. Biochem.
63
193-198
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Mechanistic studies on mercuric ion reductase and cyclohexanone oxygenase: pharmacologic and toxicologic aspects
1983
Walsh, C.; Branchaud, B.; Fox, B.; Latham, J.
Colloq. Ges. Biol. Chem. Mosbach
34
140-148
Links to other databases for 2-Hydroxycyclohexan-1-one
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