Ligand chloroacetone

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Basic Ligand Information

Molecular Structure
Picture of chloroacetone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H5ClO
chloroacetone
BULLHNJGPPOUOX-UHFFFAOYSA-N
Synonyms:
1-chloro-2-oxopropane

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cyanide + chloroacetone = (2R)-3-chloro-2-hydroxy-2-methylpropionitrile
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
20 mM, pH 6.5, 30°C, 5 h, 76% loss of activity
-
pH 8.66, 25°C, irreversible strong inhibition at concentrations of 0.1 mM and above, acetamide protects enzyme from inhibition and slowly recovers activity of inactivated enzyme
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.001
-
pH 7.1, 25°C, irreversible

References & Links

Links to other databases for chloroacetone

ChEBI
PubChem
ChEBI
PubChem