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Ligand 1,N6-Etheno-ATP Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 2 H1 6 N5 O1 3 P3
1,N6-Etheno-ATP
BKQZGVPRPNNNDW-WOUKDFQISA-N
1,N6-Ethenoadenosine 5'-triphosphate, epsilon-ATP, N6-etheno-adenosine triphosphate
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (5 results)
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N6-etheno-adenosine triphosphate + citrate + CoA = N6-etheno-adenosine diphosphate + phosphate + acetyl-CoA + oxaloacetate
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1,N6-etheno-ATP + D-fructose 6-phosphate = 1,N6-etheno-ADP + D-fructose 1,6-bisphosphate
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1,N6-ethenoadenosine 5'-triphosphate + AMP = ? + ADP
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1,N6-etheno-ATP + H2O = 1,N6-etheno-AMP + phosphate
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epsilon-ATP + H2O = ? + phosphate
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Inhibitor in Enzyme-catalyzed Reactions (3 results)
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (2 results)
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682
-
30°C, pH 6.0, presence of Ca2+
1642
-
30°C, pH 6.0, presence of Ca2+
KM Value (4 results)
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0.024
-
30°C, pH 6.0, presence of Ca2+
0.031
-
30°C, pH 6.0, presence of Ca2+
References & Links Literature References (7)
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GMP synthetase from Ehrlich ascites cells
1978
Spector, T.
Methods Enzymol.
51
219-224
Substrate specificity of T4 RNA-ligase: the role of a purine nucleotide base in forming a covalent AMP-RNA ligase complex
1993
Iuoda, B.A.; Labeikite, D.; Sasnauskene, S.I.
Biokhimiia
58
857-865
Purification and some properties of ATP citrate lyase from Penicillium spiculisporum
1973
Mahlen, A.
Eur. J. Biochem.
36
342-346
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Phosphofructokinase
1973
Bloxham, D.P.; Lardy, H.A.
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
8
239-278
Studies on adenosine triphosphate transphosphorylases. XIII. Kinetic properties of the crystalline rabbit muscle ATP-AMP transphorphorylase (adenylate kinase) and a comparison with the crystalline calf muscle and liver adenylate kinases
1978
Hamada, M.; Kuby, S.A.
Arch. Biochem. Biophys.
190
772-792
Potato tuber isoapyrases: substrate specificity, affinity labeling, and proteolytic susceptibility
2005
Kettlun, A.M.; Espinosa, V.; Garcia, L.; Valenzuela, M.A.
Phytochemistry
66
975-982
Characterization of an asymmetric occluded state of P-glycoprotein with two bound nucleotides: implications for catalysis
2010
Siarheyeva, A.; Liu, R.; Sharom, F.J.
J. Biol. Chem.
285
7575-7586
Links to other databases for 1,N6-Etheno-ATP