Ligand Xanthosine

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Basic Ligand Information

Molecular Structure
Picture of Xanthosine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H12N4O6
Xanthosine
UBORTCNDUKBEOP-UUOKFMHZSA-N
Synonyms:
9-deoxyribosylxanthine


Show all pahtways known for Show all BRENDA pathways known for Xanthosine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + xanthosine = S-adenosyl-L-homocysteine + 7-methylxanthosine
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xanthosine + phosphate = xanthine + alpha-D-ribose 1-phosphate
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In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
guanosine + H2O = xanthosine + NH3
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Substrate in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
xanthosine + O2 = 9-riburonosylxanthine + H2O
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xanthosine + NAD+ + H2O = ? + NADH
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S-adenosyl-L-methionine + xanthosine = S-adenosyl-L-homocysteine + 7-methylxanthosine
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ATP + xanthosine = ADP + XMP
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xanthosine + H2O = D-ribose + xanthine
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xanthosine + H2O = xanthine + D-ribose
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Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
inosine + NAD+ + H2O = xanthosine + NADH
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inosine + xanthine = hypoxanthine + xanthosine
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guanosine + H2O = xanthosine + NH3
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guanosine + H2O = xanthosine + NH3
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guanosine + H2O = xanthosine + NH3
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
poor inhibitor of phosphorolysis of guanosine
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weak inhibition
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potent inhibitor
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3D Structure of Enzyme-Ligand-Complex (PDB) (2 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (20 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (37 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for Xanthosine

ChEBI
PubChem
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PubChem