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Ligand all-trans-octaprenyl diphosphate

Basic Ligand Information

Molecular Structure

Show all BRENDA pathways known for all-trans-octaprenyl diphosphate

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.5.1.74

octaprenyl diphosphate + 1,4-dihydroxy-2-naphthoate = a demethylmenaquinol + diphosphate + CO2

737563

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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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Show Natural Product (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.5.1.90

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate

0

-

Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Substrate (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.5.1.39

octaprenyl diphosphate + 4-hydroxybenzoate = 4-hydroxy-3-octaprenylbenzoate + diphosphate

704240, 705223

-

2.5.1.74

octaprenyl diphosphate + 1,4-dihydroxy-2-naphthoate = a demethylmenaquinol + diphosphate + CO2

737563

-

Product in Enzyme-catalyzed Reactions (8 results)

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Show Product (8 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.5.1.10

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate

0

-

2.5.1.86

(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + decaprenyl diphosphate + nonaprenyl diphosphate + octaprenyl diphosphate

0

-

2.5.1.86

geranyl diphosphate + isopentenyl diphosphate = diphosphate + decaprenyl diphosphate + nonaprenyl diphosphate + octaprenyl diphosphate

0

-

2.5.1.86

geranylgeranyl diphosphate + isopentenyl diphosphate = diphosphate + decaprenyl diphosphate + octaprenyl diphosphate + nonaprenyl diphosphate

0

-

2.5.1.86

neryl diphosphate + isopentenyl diphosphate = diphosphate + decaprenyl diphosphate + nonaprenyl diphosphate + octaprenyl diphosphate

0

-

2.5.1.90

(2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate

0

-

2.5.1.90

dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + octaprenyl diphosphate + nonaprenyl diphosphate

0

-

2.5.1.86

4 entries

2.5.1.90

2 entries

2.5.1.91

(2E,6E,10E)-geranylgeranyl diphosphate + isopentenyl diphosphate = diphosphate + octaprenyl diphosphate

0

-

Enzyme Kinetic Parameters

References & Links

Literature References (3)

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Show Reference (3 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

704240

4552989

Biochemical and genetic studies on ubiquinone biosynthesis in Escherichia coli K-12 4-hydroxybenzoate octaprenyltransferase

1972

Young, I.G.; Leppik, R.A.; Hamilton, J.A.; Gibson, F.

J. Bacteriol.

110

18-25

705223

15597200

Modeling the E. coli 4-hydroxybenzoic acid oligoprenyltransferase (ubiA transferase) and characterization of potential active sites.

2004

Brauer, L.; Brandt, W.; Wessjohann, L.A.

J. Mol. Model.

10

317-327

737563

25772016

Isolation and functional analysis of McMenA, a gene encoding a 1,4-dihydroxy-2-naphthoate octaprenyltransferase in Mylabris cichorii

2015

Liao, Y.F.; Wang, Y.; Huang, Y.; Zha, S.F.; Liu, J.J.; Wang, Z.K.; Yin, Y.P.; Liao, Y.F.; Wang, Y.

Arch. Insect Biochem. Physiol.

89

127-137

Links to other databases for all-trans-octaprenyl diphosphate

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Show Links (1 entry)

ChEBI

PubChem