Ligand reduced megaredoxin
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Basic Ligand Information
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (7 results)
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11-deoxycorticosterone + reduced megaredoxin + O2 = 15beta-hydroxy-11-deoxycorticosterone + oxidized megaredoxin + H2O
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17alpha-hydroxyprogesterone + reduced megaredoxin + O2 = (15beta,17alpha)-15,17-dihydroxyprogesterone + oxidized megaredoxin + H2O
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20alpha-dihydroprogesterone + reduced megaredoxin + O2 = (15beta,20alpha)-15-hydroxy-20-dihydroprogesterone + oxidized megaredoxin + H2O
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4-androstene-3,17-dione + reduced megaredoxin + O2 = 15beta-hydroxyandrostene-3,17-dione + oxidized megaredoxin + H2O
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corticosterone + reduced megaredoxin + O2 = 15beta-hydroxycorticosterone + oxidized megaredoxin + H2O
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progesterone + reduced megaredoxin + O2 = 15beta-hydroxyprogesterone + oxidized megaredoxin + H2O
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testosterone + reduced megaredoxin + O2 = 15beta-hydroxytestosterone + oxidized megaredoxin + H2O
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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Function and engineering of the 15beta-hydroxylase CYP106A2
2006
Virus, C.; Lisurek, M.; Simgen, B.; Hannemann, F.; Bernhardt, R.
Biochem. Soc. Trans.
34
1215-1218
Characterization of a cytochrome P-450-dependent steroid hydroxylase system present in Bacillus megaterium
1976
Berg, A.; Gustafsson, J.A.; Ingelman-Sundberg, M.
J. Biol. Chem.
251
2831-2838
Links to other databases for reduced megaredoxin