Ligand quercetin-3-O-methylether

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Basic Ligand Information

Molecular Structure
Picture of quercetin-3-O-methylether (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C16H12O7
quercetin-3-O-methylether
WEPBGSIAWZTEJR-UHFFFAOYSA-N
Synonyms:
3',4',5,7-tetrahydroxy-3-methoxyflavone, 3-methoxy-5,7,3',4'-tetrahydroxyflavone, 3-methylquercetin, 3-O-methyl-quercetin, 3-O-methyl quercetin, 3-O-methylquercetin, 5,7,3',4'-tetrahydroxy-3-methoxyflavone

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + 3',4',5,7-tetrahydroxy-3-methoxyflavone = S-adenosyl-L-homocysteine + 3',4',5-trihydroxy-3,7-dimethoxyflavone
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + 3-O-methylquercetin = S-adenosyl-L-homocysteine + ?
show the reaction diagram
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S-adenosyl-L-methionine + 3',4',5,7-tetrahydroxy-3-methoxyflavone = S-adenosyl-L-homocysteine + 3',4',5-trihydroxy-3,7-dimethoxyflavone
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
noncompetitive inhibitor with respect to both S-adenosyl-L-methionine and quercetin
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Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.007
-
-

IC50 Value (4 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0869
-
PDE5
0.0285
-
PDE4

References & Links

Links to other databases for quercetin-3-O-methylether

ChEBI
PubChem
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PubChem