Ligand S-nitroso-L-cysteinylglycine
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Basic Ligand Information
Molecular Structure

C5H9N3O4S
S-nitroso-L-cysteinylglycine
UOHAKHBEJRPHQZ-VKHMYHEASA-N
S-nitroso-cysteinylglycine, S-nitrosocysteinylglycine
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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S-nitrosocysteinylglycine + H2O = S-nitrosocysteine + glycine
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Product in Enzyme-catalyzed Reactions (1 result)
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S-nitroso-glutathione + glycyl-glycine = S-nitroso-cysteinylglycine + gamma-L-glutamyl-glycyl-glycine
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Inhibitor in Enzyme-catalyzed Reactions (1 result)
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inactivation, prevented by pretreatment with ATP and L-SR-buthionine sulfoximine in absence of Mg2+
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase
1999
Griffith, O.W.; Mulcahy, R.T.
Adv. Enzymol. Relat. Areas Mol. Biol.
73
209-267
Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver
2003
Jösch, C.; Klotz, L.O.; Sies, H.
Biol. Chem.
384
213-218
Links to other databases for S-nitroso-L-cysteinylglycine