Ligand 6-fluoro-tryptamine

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Basic Ligand Information

Molecular Structure
Picture of 6-fluoro-tryptamine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H11FN2
6-fluoro-tryptamine
BQTOKMYKZPCPRW-UHFFFAOYSA-N
Synonyms:
2-(6-fluoro-1H-indol-3-yl)ethanamine, 6-fluorotryptamine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
acetyl-CoA + 6-fluorotryptamine = CoA + N-acetyl-6-fluorotryptamine
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE
a drug causing head-twitch response, IC50: 0.00018 mM
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
HPLC, neutral pH, micromolar to low millimolar substrate concentrations
0.0093
-
mutant V208A
wild-type enzyme

KM Value (3 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
HPLC, neutral pH, micromolar to low millimolar substrate concentrations
0.0089
-
mutant V208A
0.356
-
wild-type enzyme
0.136
-

IC50 Value (1 result)

COMMENTARY
EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
LITERATURE
a drug causing head-twitch response, IC50: 0.00018 mM
0.00018
-

References & Links

Links to other databases for 6-fluoro-tryptamine

ChEBI
PubChem
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PubChem