Ligand Ala-Ala

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Basic Ligand Information

Molecular Structure
Picture of Ala-Ala (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H12N2O3
Ala-Ala
DEFJQIDDEAULHB-IMJSIDKUSA-N
Synonyms:
AA, dialanine, L-Ala-L-Ala, L-Ala-L-Ala[side 2], L-alanyl-L-alanine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (16 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Ala-Ala + H2O = Ala + Ala
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Ala-Ala + H2O = L-alanine + L-alanine
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Ala-Ala + H2O = Ala + Ala
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Ala-Ala + H2O = Ala + Ala
show the reaction diagram
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L-Ala-L-Ala + H2O = L-Ala + L-Ala
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Ala-Ala + H2O = Ala + Ala
show the reaction diagram
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Ala-Ala + H2O = Ala + Ala
show the reaction diagram
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Ala-Ala + H2O = Ala + Ala
show the reaction diagram
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L-Ala-L-Ala + H2O = Ala-Ala-Ala-Ala
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Ala-Ala + H2O = Ala + Ala
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Ala-Ala + H2O = Ala + Ala
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Abz-LPETGG-Dap(Dnp)-NH2 + Ala-Ala = Abz-LPETAA + GG-Dap(Dnp)-NH2
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L-Ala-L-Ala = L-Ala-D-Ala
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ATP + H2O + L-Ala-L-Ala/in = ADP + phosphate + L-Ala-L-Ala/out
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Product in Enzyme-catalyzed Reactions (94 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5'AUCAAAGAAA + H2O = 5'AUCAAAGA + AA
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(Ala)3 + H2O = Ala + Ala-Ala
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Met-Ala-Ala + H2O = Met + Ala-Ala
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D-Ala-L-Ala-L-Ala + H2O = D-Ala + Ala-Ala
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L-alanyl-L-alanyl-L-7-amido-4-carbamoylmethylcoumarin + H2O = L-alanyl-L-alanine + 7-amino-4-carbamoylmethylcoumarin
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Tyr-Ala-Ala + H2O = Tyr + Ala-Ala
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Ala-Ala 4-nitroanilide + H2O = Ala-Ala + 4-nitroaniline
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N-acetyl-Ala-Ala-Ala + H2O = N-acetyl-L-alanine + Ala-Ala
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Ala-Ala-Ala + H2O = Ala + Ala-Ala
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Ala-Ala 4-nitroanilide + H2O = Ala-Ala + 4-nitroaniline
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Ala-Ala-p-nitroanilide + H2O = Ala-Ala + p-nitroaniline
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Met-Ala-Ala + H2O = Met + Ala-Ala
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L-alanyl-L-alanyl-4-nitroanilide + H2O = L-alanyl-L-alanine + 4-nitroaniline
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Benzyloxycarbonyl-Lys-Ala-Ala + H2O = Benzyloxycarbonyl-Lys + Ala-Ala
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ATP + alanine + alanine = ADP + phosphate + L-alanyl-L-alanine
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ATP + H2O + L-Ala-L-Ala/in = ADP + phosphate + L-Ala-L-Ala/out
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ATP + H2O + L-Ala-L-Ala-[dipeptide-binding protein][side 1] = ADP + phosphate + L-Ala-L-Ala[side 2] + [dipeptide-binding protein][side 1]
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Inhibitor in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibits hyrolysis of Ala-2-naphthylamide
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hydrolysis of Gly-Pro-4-nitroanilide
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.18
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pH 7.5, 85°C

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
39.9
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pH 7.5, 85°C
2.8
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Ki Value (9 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.9
-
hydrolysis of Ala-2-naphthylamide
98
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pH 8.0, 37°C

IC50 Value (7 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for Ala-Ala

ChEBI
PubChem
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PubChem