Ligand hyperoside

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Basic Ligand Information

Molecular Structure
Picture of hyperoside (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C21H20O12
hyperoside
OVSQVDMCBVZWGM-DTGCRPNFSA-N
Synonyms:
2-(3',4'-dihydroxyphenyl)-5,7-dihydroxy-3-beta-D-galactosyl-4H-chromen-4-one, hyperin, hyperosid, quercetin 3-O-beta-D-galactoside, quercetin 3-O-galactoside

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
malonyl-CoA + hyperoside = ?
show the reaction diagram
-
UDP-glucose + quercetin 3-O-galactoside = UDP + quercetin 3-O-beta-D-galactosyl-(1->6)-beta-D-glucoside
show the reaction diagram
-
UDP-D-xylose + quercetin 3-O-galactoside = UDP + quercetin 3-O-xylosylgalactoside
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-alpha-D-galactose + quercetin = UDP + hyperoside
show the reaction diagram
-
-
UDP-galactose + quercetin = UDP + quercetin 3-O-beta-D-galactoside
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50: 0.0746 mM
-
IC50: 0.2 mM
-
slight inhibition
-
0.05 mM, 41.8% inhibition
-
below 5% inhibition of rhGLO I at 0.1 mM
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
82.3
-
pH 6, 43°C, reverse reaction

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.00265
-
pH 6, 43°C, reverse reaction

IC50 Value (5 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.01995
-
pH 7.0 and 37°C
0.0746
-
IC50: 0.0746 mM
0.0118
-
-
0.2
-
IC50: 0.2 mM
0.043
-
-

References & Links

Links to other databases for hyperoside

ChEBI
PubChem
ChEBI
PubChem