Ligand 7-chloro-L-tryptophan

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of 7-chloro-L-tryptophan (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C11H11ClN2O2
7-chloro-L-tryptophan
DMQFGLHRDFQKNR-VIFPVBQESA-N
Synonyms:
7-chloro-tryptophan, 7-chlorotryptophan

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7-chloro-L-tryptophan + FADH2 + chloride + O2 + H+ = 6,7-dichloro-L-tryptophan + FAD + 2 H2O
show the reaction diagram
-
7-chloro-L-tryptophan + FADH2 + Cl- + O2 + H+ = 6,7-dichloro-L-tryptophan + FAD + 2 H2O
show the reaction diagram
-
7-chloroindole-3-pyruvic acid + 7-chlorotryptophan + O2 = 11,11'-dichlorochromopyrrolic acid + NH3 + H2O
show the reaction diagram
-
7-chloro-L-tryptophan + O2 = 2-imino-3-(7-chloroindol-3-yl)propanoate + H2O2
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7-chloro-L-tryptophan + FADH2 + chloride + O2 + H+ = 6,7-dichloro-L-tryptophan + FAD + 2 H2O
show the reaction diagram
-
7-chloro-L-tryptophan + FADH2 + Cl- + O2 + H+ = 6,7-dichloro-L-tryptophan + FAD + 2 H2O
show the reaction diagram
-
7-chloroindole-3-pyruvic acid + 7-chlorotryptophan + O2 = 11,11'-dichlorochromopyrrolic acid + NH3 + H2O
show the reaction diagram
-
7-chloro-L-tryptophan + O2 = 2-imino-3-(7-chloroindol-3-yl)propanoate + H2O2
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-serine + 7-chloroindole = 7-chlorotryptophan + H2O
show the reaction diagram
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.023
-
pH 7.0, 22°C
0.664
-
pH 7.8, 30°C

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.114
-
pH 7.0, 22°C
0.088
-
pH 7.8, 30°C

References & Links

Links to other databases for 7-chloro-L-tryptophan

ChEBI
PubChem
-
PubChem