Ligand 16-hydroxypalmitic acid

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Basic Ligand Information

Molecular Structure
Picture of 16-hydroxypalmitic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C16H32O3
16-hydroxypalmitic acid
UGAGPNKCDRTDHP-UHFFFAOYSA-N
Synonyms:
16-hydroxyhexadecanoate, 16-hydroxyhexadecanoic acid, 16-hydroxypalmitate, 18-hydroxypalmitic acid, omega-hydroxypalmitic acid

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
palmitic acid + [reduced NADPH-hemoprotein reductase] + O2 = 16-hydroxypalmitic acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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cutin + H2O = 16-hydroxyhexadecanoic acid + 10,16-dihydroxyhexadecanoic acid + 9,10,18-trihydroxyoctadecanoic acid
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
16-hydroxyhexadecanoate + NAD+ = 16-oxohexadecanoic acid + NADH
show the reaction diagram
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16-hydroxyhexadecanoic acid + O2 = ?
show the reaction diagram
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omega-hydroxypalmitic acid + lyso-GM1a = ? + H2O
show the reaction diagram
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ATP + 16-hydroxypalmitic acid + CoA = AMP + diphosphate + 16-hydroxypalmitoyl-CoA
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
palmitic acid + [reduced NADPH-hemoprotein reductase] + O2 = 16-hydroxypalmitic acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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-
palmitic acid + [reduced NADPH-hemoprotein reductase] + O2 = 16-hydroxypalmitic acid + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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palmitic acid + NAD(P)H + H+ + O2 = 16-hydroxyhexadecanoic acid + NAD(P)+ + H2O
show the reaction diagram
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cutin + H2O = 16-hydroxyhexadecanoic acid + 10,16-dihydroxyhexadecanoic acid + 9,10,18-trihydroxyoctadecanoic acid
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
is strongly induced in vitro by cutin monomer 16-hydroxyhexadecanoic acid
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
6.17
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KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.06
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0.1 M glycine-NaOH buffer, pH 10.0, 25°C
0.0314
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isoenzyme LACS2

References & Links

Links to other databases for 16-hydroxypalmitic acid

ChEBI
PubChem
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PubChem