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Ligand ubiquinone-1

Basic Ligand Information

Molecular Structure

Pathway Source

Pathways

BRENDA

glycogen metabolism, oxidative phosphorylation, pyrimidine metabolism, ubiquinone biosynthesis

KEGG

Biosynthesis of cofactors, Oxidative phosphorylation, Two-component system

MetaCyc

2-chloroacrylate degradation I, aerobic respiration I (cytochrome c), aerobic respiration II (cytochrome c) (yeast), aerobic respiration III (alternative oxidase pathway), ammonia oxidation IV (autotrophic ammonia oxidizers), caffeine degradation V (bacteria, via trimethylurate), D-lactate to cytochrome bo oxidase electron transfer, Fe(II) oxidation, glucose and glucose-1-phosphate degradation, glucose degradation (oxidative), glycerol-3-phosphate to cytochrome bo oxidase electron transfer, heme b biosynthesis V (aerobic), L-ascorbate biosynthesis VIII (engineered pathway), long chain fatty acid ester synthesis (engineered), mitochondrial NADPH production (yeast), NAD(P)/NADPH interconversion, NADH to cytochrome bd oxidase electron transfer I, NADH to cytochrome bd oxidase electron transfer II, NADH to cytochrome bo oxidase electron transfer I, NADH to cytochrome bo oxidase electron transfer II, nitrate reduction VIIIb (dissimilatory), nitrate reduction X (dissimilatory, periplasmic), proline to cytochrome bo oxidase electron transfer, pyruvate to cytochrome bd oxidase electron transfer, pyruvate to cytochrome bo oxidase electron transfer, succinate to cytochrome bd oxidase electron transfer, succinate to cytochrome bo oxidase electron transfer, TCA cycle III (animals) more

Show all BRENDA pathways known for ubiquinone-1

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (60 results)

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Show Natural Substrate (60 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.5.14

D-fructose + ubiquinone = 5-dehydro-D-fructose + ubiquinol

740369

-

1.1.5.2

beta-D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol

654863

-

1.1.5.2

D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol

671165, 674663, 712800, 739914, 654449, 725196, 739873, 740191, 740304, 740321, 740441, 740577, 740933, 724022, 739872, 724081, 655127, 671548, 725039, 724852, 741032, 654864, 654865

-

1.1.5.3

sn-glycerol 3-phosphate + coenzyme Q1 = dihydroxyacetone phosphate + reduced coenzyme Q1

740095

-

1.1.5.3

sn-glycerol 3-phosphate + ubiquinone = glycerone phosphate + ubiquinol

741302

-

1.1.5.2

2 entries

1.1.5.3

2 entries

1.1.5.4

(S)-malate + ubiquinone = oxaloacetate + ubiquinol

723124, 762760

-

1.1.5.5

ethanol + ubiquinone = acetaldehyde + ubiquinol

725298, 724402, 724044, 724042, 725154, 726014, 731507, 724837, 724087, 685685

-

1.1.5.5

ethanol + ubiquinone-1 = acetaldehyde + ubiquinol-1

685310

-

1.1.5.5

2 entries

1.1.99.1

choline + coenzyme Q1 = betaine aldehyde + reduced coenzyme Q1

389886

-

1.1.99.22

(S)-2-hydroxyglutarate + ubiquinone = 2-oxoglutarate + ubiquinol

721866

-

1.17.5.1

phenylacetyl-CoA + H2O + ubiquinone = phenylglyoxylyl-CoA + ubiquinol

644661

-

1.17.5.2

caffeine + ubiquinone + H2O = 1,3,7-trimethylurate + ubiquinol

745135

-

1.2.5.1

pyruvate + ubiquinone + H2O = acetate + CO2 + ubiquinol

741301, 724036, 724069

-

1.2.5.2

acetaldehyde + ubiquinone = acetate + ubiquinol

687166

-

1.2.5.3

CO + ubiquinone + H2O = CO2 + ubiquinol

736437, 736514

-

1.3.5.1

succinate + ubiquinone = fumarate + ubiquinol

391134, 391143, 655570, 685357, 654092, 655573, 656003, 657349, 674644, 685281, 391137, 391139, 654444, 656605, 687110, 687955, 687966, 688882, 689710, 724698, 657158, 654819, 655999, 656178, 656275, 656276, 685323, 2877, 391136, 391128, 762895, 391082, 674762, 686649, 687483, 687015, 687608, 688964

1zoy, 3D-view

1.3.5.1

succinate + ubiquinone = fumarate + ubiquinol

391134, 391143, 655570, 685357, 654092, 655573, 656003, 657349, 674644, 685281, 391137, 391139, 654444, 656605, 687110, 687955, 687966, 688882, 689710, 724698, 657158, 654819, 655999, 656178, 656275, 656276, 685323, 2877, 391136, 391128, 762895, 391082, 674762, 686649, 687483, 687015, 687608, 688964

5c3j, 3D-view

1.3.5.1

2 entries

1.3.5.2

(S)-dihydroorotate + ubiquinone = orotate + ubiquinol

390925, 763351, 390924, 390926, 390922, 390929

-

1.3.5.3

protoporphyrinogen IX + 3 ubiquinone = protoporphyrin IX + 3 ubiquinol

726366

-

1.4.99.6

D-Pro + H2O + coenzyme Q1 = ?

695533

-

1.5.5.1

reduced electron-transferring flavoprotein + ubiquinone = electron-transferring flavoprotein + ubiquinol

724446, 713271, 743186, 742306, 742902, 724410, 726447, 743249

-

1.5.5.1

reduced electron-transferring-flavoprotein + ubiquinone = electron-transferring-flavoprotein + ubiquinol

655306, 654538

-

1.5.5.1

2 entries

1.6.5.2

NADH + H+ + ubiquinone = NAD+ + ubiquinone

700003

-

1.6.5.9

NADH + H+ + ubiquinone = NAD+ + ubiquinol

724488, 392700, 726384, 715710, 726096

-

1.7.5.1

nitrite + ubiquinone + H2O = nitrate + ubiquinol

742333

-

1.8.1.4

ubiquinone + NAD(P)H = ubiquinol + NAD(P)+

658600, 658231

-

1.8.5.4

sulfide + ubiquinone-1 = sulfur + ubiquinol-1

724350

-

1.8.5.8

hydrogen sulfide + glutathione + ubiquinone = S-sulfanylglutathione + ubiquinol

764525

-

1.8.5.9

a [DsbA protein] with reduced L-cysteine residues + ubiquinone = a [DsbA protein] carrying a disulfide bond + ubiquinol

755706, 756115, 757693

-

1.8.5.9

a [DsbB protein] with reduced L-cysteine residues + ubiquinone = a [DsbB protein] carrying a disulfide bond + ubiquinol

756115

-

1.8.5.9

[DsbA protein] with reduced L-cysteine residues + ubiquinone = [DsbA protein] carrying a disulfide bond + ubiquinol

757146, 757516, 758211, 758288, 756589

-

1.8.5.9

[DsbB protein] with reduced L-cysteine residues + ubiquinone = [DsbB protein] carrying a disulfide bond + ubiquinol

757146, 756589

-

1.8.5.9

[DsbA protein] with reduced L-cysteine residues + ubiquinone-1 = [DsbA protein] carrying a disulfide bond + ubiquinol-1

756909

-

1.8.5.9

[DsbB protein] with reduced L-cysteine residues + ubiquinone-1 = [DsbB protein] carrying a disulfide bond + ubiquinol-1

756909

-

1.8.5.9

6 entries

1.8.99.B2

2 thiosulfate + ubiquinone = tetrathionate + ubiquinol

742121

-

7.1.1.2

NADH + H+ + ubiquinone = NAD+ + ubiquinol

696270, 714303, 696380, 697166, 696147

7v2r, 3D-view

7.1.1.2

NADH + ubiquinone + 6 H+[side 1] = NAD+ + ubiquinol + 7 H+[side 2]

724420, 724310, 725142, 725443, 725517, 724252, 724383, 724564, 725003, 725491

7v2r, 3D-view

7.1.1.2

NADH + ubiquinone = ?

392717, 392692, 392705, 392711, 392707, 392714, 392700, 392701, 392681, 392690, 392723

7v2r, 3D-view

7.2.1.1

deamino-NADH + H+ + ubiquinone + 2 Na+/in = deamino-NAD+ + ubiquinol + 2 Na+/out

711293

8evu, 3D-view

7.2.1.1

deamino-NADH + H+ + ubiquinone + 2 Na+/in = deamino-NAD+ + ubiquinol + 2 Na+/out

711293

8ew3, 3D-view

7.2.1.1

deamino-NADH + H+ + ubiquinone + n Na+/in = deamino-NAD+ + ubiquinol + n Na+/out

711991

8evu, 3D-view

7.2.1.1

deamino-NADH + H+ + ubiquinone + n Na+/in = deamino-NAD+ + ubiquinol + n Na+/out

711991

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + 2 Na+/in = NAD+ + ubiquinol + 2 Na+/out

711269, 711293

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + 2 Na+/in = NAD+ + ubiquinol + 2 Na+/out

711269, 711293

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + n Na+/in = NAD+ + ubiquinol + n Na+/out

742842, 710746, 713414, 725433, 725448, 725538, 711991, 711995, 711996, 711997, 725402, 725481, 725539, 712407, 724251

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + n Na+/in = NAD+ + ubiquinol + n Na+/out

742842, 710746, 713414, 725433, 725448, 725538, 711991, 711995, 711996, 711997, 725402, 725481, 725539, 712407, 724251

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + Na+/in = NAD+ + ubiquinol + Na+/out

712274

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + Na+/in = NAD+ + ubiquinol + Na+/out

712274

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone = NAD+ + ubiquinol

700061, 698995, 696362

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone = NAD+ + ubiquinol

700061, 698995, 696362

8ew3, 3D-view

7.2.1.1

NADH + ubiquinone = ?

392712, 392713, 392715, 392695, 392716

8evu, 3D-view

7.2.1.1

NADH + ubiquinone = ?

392712, 392713, 392715, 392695, 392716

8ew3, 3D-view

7.2.1.1

thio-NADH + H+ + ubiquinone + 2 Na+/in = thio-NAD+ + ubiquinol + 2 Na+/out

711293

8evu, 3D-view

7.2.1.1

thio-NADH + H+ + ubiquinone + 2 Na+/in = thio-NAD+ + ubiquinol + 2 Na+/out

711293

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone-1 + n Na+/in = NAD+ + ubiquinol-1 + n Na+/out

658029

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone-1 + n Na+/in = NAD+ + ubiquinol-1 + n Na+/out

658029

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone-1 = NAD+ + ubiquinol-1

696386

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone-1 = NAD+ + ubiquinol-1

696386

8ew3, 3D-view

7.2.1.1

NADH + ubiquinone-1 = NAD+ + ubiquinol-1

671351

8evu, 3D-view

7.2.1.1

NADH + ubiquinone-1 = NAD+ + ubiquinol-1

671351

8ew3, 3D-view

7.1.1.2

3 entries

7.2.1.1

22 entries

In Vivo Product in Enzyme-catalyzed Reactions (13 results)

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Show Natural Product (13 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.5.5

acetaldehyde + ubiquinol = ethanol + ubiquinone

0

-

1.10.3.11

2 ubiquinol + O2 = 2 ubiquinone + 2 H2O

0

-

1.10.3.11

2 ubiquinol-1 + O2 = 2 ubiquinone-1 + 2 H2O

0

-

1.10.3.11

ubiquinol + O2 = ubiquinone + H2O

0

-

1.10.3.11

3 entries

1.10.3.17

2 O2 + ubiquinol = 2 superoxide + ubiquinone + 2 H+

0

-

1.6.5.2

NADH + H+ + ubiquinone = NAD+ + ubiquinone

0

-

7.1.1.3

ubiquinol + O2 + H+[side 1] = ubiquinone + H2O + H+[side 2]

0

-

7.1.1.7

2 ubiquinol + O2 + 4 H+[side 1] = 2 ubiquinone + 2 H2O + 4 H+[side 2]

0

-

7.1.1.7

ubiquinol + O2 + H+[side 1] = ubiquinone + H2O + H+[side 2]

0

-

7.1.1.8

ubiquinol + 2 ferricytochrome c = ubiquinone + 2 ferrocytochrome c + 2 H+

0

-

7.1.1.8

ubiquinol + 2 ferricytochrome c552 = ubiquinone + 2 ferrocytochrome c552 + 2 H+

0

-

7.1.1.8

ubiquinol + ferricytochrome c = ubiquinone + ferrocytochrome c

0

-

7.1.1.8

ubiquinol + ferricytochrome c = ubiquinone + ferrocytochrome c + H+

0

-

7.1.1.7

2 entries

7.1.1.8

4 entries

Substrate in Enzyme-catalyzed Reactions (207 results)

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Show Substrate (207 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.1

ubiquinone + NADH + H+ = ubiquinol + NAD+

760376

-

1.1.1.184

ubiquinone-1 + NADPH = ?

347749

-

1.1.5.10

D-lactate + ubiquinone = pyruvate + ubiquinol

724205

-

1.1.5.12

D-lactate + ubiquinone 1 = pyruvate + reduced ubiquinone 1

740030

-

1.1.5.13

L-2-hydroxyglutarate + ubiquinone-1 = 2-oxoglutarate + ubiquinol-1

754854

-

1.1.5.14

D-fructose + ubiquinone = 5-dehydro-D-fructose + ubiquinol

740369

-

1.1.5.2

2-deoxy-D-glucose + ubiquinone = 2-deoxy-D-glucono-1,5-lactone + ubiquinol

724081, 654865, 655101, 655363, 741370

-

1.1.5.2

3-methyl-alpha-methyl-D-glucopyranose + ubiquinone = D-xylono-1,5-lactone + ubiquinol

741370

-

1.1.5.2

3-O-methyl-D-glucose + ubiquinone = 3-O-methyl-D-glucono-1,5-lactone + ubiquinol

654398, 655101, 654865, 655363

-

1.1.5.2

allose + ubiquinone = ? + ubiquinol

654398, 655101, 655363

-

1.1.5.2

beta-D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol

654863

-

1.1.5.2

cellobiose + ubiquinone = ?

739873

-

1.1.5.2

cellobiose + ubiquinone = ? + ubiquinol

654938, 655363

-

1.1.5.2

D-allose + ubiquinone = ?

739873

-

1.1.5.2

D-allose + ubiquinone = ? + ubiquinol

724081

-

1.1.5.2

D-fucose + ubiquinone = ? + ubiquinol

724081

-

1.1.5.2

D-galactose + ubiquinone = ?

671548, 739873

-

1.1.5.2

D-galactose + ubiquinone = D-galactono-1,5-lactone + ubiquinol

655101, 654938, 654865, 654398, 655363, 741370

-

1.1.5.2

D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol

655101, 671165, 674663, 712800, 739914, 654449, 655791, 655929, 725196, 739873, 740191, 740304, 740321, 740441, 740577, 740933, 724022, 739872, 724081, 654780, 654936, 654865, 654864, 655097, 655127, 671548, 725039, 654938, 654947, 724852, 741032, 654398, 655363

-

1.1.5.2

D-lyxose + ubiquinone = ?

739873

-

1.1.5.2

D-mannose + ubiquinone = ?

739873

-

1.1.5.2

D-mannose + ubiquinone = ? + ubiquinol

654865, 655363

-

1.1.5.2

D-ribose + ubiquinone = ?

739873

-

1.1.5.2

D-ribose + ubiquinone = ? + ubiquinol

654865

-

1.1.5.2

D-xylose + ubiquinone = ?

739873

-

1.1.5.2

D-xylose + ubiquinone = D-xylono-1,5-lactone + ubiquinol

655101, 724081, 654865, 655363, 741370

-

1.1.5.2

L-arabinose + ubiquinone = ?

739873

-

1.1.5.2

L-arabinose + ubiquinone = L-arabino-1,5-lactone + ubiquinol

654938, 654865

-

1.1.5.2

lactose + ubiquinone = ?

739873, 671548

-

1.1.5.2

lactose + ubiquinone = ? + ubiquinol

639212, 654398, 655101, 654938, 655363

-

1.1.5.2

maltose + ubiquinone = ?

739873, 671548

-

1.1.5.2

maltose + ubiquinone = ? + ubiquinol

654398, 655101, 674663, 654938, 655363

-

1.1.5.2

melibiose + ubiquinone = ?

739873

-

1.1.5.2

D-glucose + ubiquinone Q1 = D-glucono-1,5-lactone + ?

639201, 639199

-

1.1.5.2

D-glucose + ubiquinone Q1 = D-glucono-1,5-lactone + ubiquinol Q1

741370

-

1.1.5.3

sn-glycerol 3-phosphate + coenzyme Q1 = dihydroxyacetone phosphate + reduced coenzyme Q1

740095

-

1.1.5.3

sn-glycerol 3-phosphate + coenzyme Q1 = glycerone phosphate + reduced coenzyme Q1

287802, 287806, 287809, 690607, 287805

-

1.1.5.3

sn-glycerol 3-phosphate + ubiquinone = glycerone phosphate + ubiquinol

741302

-

1.1.5.4

(S)-malate + ubiquinone = oxaloacetate + ubiquinol

722575, 723124, 762760

-

1.1.5.4

(S)-malate + ubiquinone-1 = oxaloacetate + reduced ubiquinone-1

287733

-

1.1.5.4

(S)-malate + ubiquinone-1 = oxaloacetate + ubiquinol-1

698670

-

1.1.5.5

1,3-butandiol + ubiquinone = ? + ubiquinol

725298

-

1.1.5.5

1,3-propandiol + ubiquinone = ? + ubiquinol

725298

-

1.1.5.5

1-butanol + ubiquinone = butanal + ubiquinol

725298

-

1.1.5.5

1-hexanol + ubiquinone = hexanal + ubiquinol

725298

-

1.1.5.5

1-octanol + ubiquinone = octanal + ubiquinol

725298

-

1.1.5.5

1-pentanol + ubiquinone = pentanal + ubiquinol

725298

-

1.1.5.5

1-propanol + ubiquinone = propanal + ubiquinol

725298

-

1.1.5.5

2-butanol + ubiquinone = 2-butanone + ubiquinol

725298

-

1.1.5.5

2-propanol + ubiquinone = acetone + ubiquinol

725298

-

1.1.5.5

3-methyl-1-butanol + ubiquinone = 3-methyl-1-butanal + ubiquinol

725298

-

1.1.5.5

citronellol + ubiquinone = citronellal + ubiquinol

725298

-

1.1.5.5

ethanol + ubiquinone = acetaldehyde + ubiquinol

725298, 724402, 724044, 724042, 725154, 726014, 731507, 724837, 724087, 685685

-

1.1.5.5

geraniol + ubiquinone = geranial + ubiquinol

725298

-

1.1.5.5

ethanol + ubiquinone-1 = acetaldehyde + ubiquinol-1

685310, 711032

-

1.1.5.2

29 entries

1.1.5.3

3 entries

1.1.5.4

3 entries

1.1.5.5

14 entries

1.1.5.9

D-glucose + coenzyme Q1 = D-glucono-1,5-lactone + reduced coenzyme Q1

348276

-

1.1.99.1

choline + coenzyme Q1 = betaine aldehyde + reduced coenzyme Q1

389886

-

1.1.99.18

cellobiose + ubiquinone = cellobiono-1,5-lactone + reduced ubiquinone

655002, 673525

-

1.1.99.22

(S)-2-hydroxyglutarate + ubiquinone = 2-oxoglutarate + ubiquinol

721866

-

1.1.99.3

D-gluconate + coenzyme Q1 = 2-oxogluconate + ?

389919

-

1.10.5.1

N-benzyldihydronicotinamide + coenzyme Q1 = N-benzylnicotinamide + ?

695860

-

1.10.5.1

N-benzyldihydronicotinamide + oxidized coenzyme Q1 = N-benzylnicointamide + reduced coenzyme Q1

711729

-

1.10.5.1

2 entries

1.17.5.1

phenylacetyl-CoA + H2O + ubiquinone = phenylglyoxylyl-CoA + ubiquinol

644661

-

1.17.5.2

caffeine + ubiquinone + H2O = 1,3,7-trimethylurate + ubiquinol

745135

-

1.2.5.1

pyruvate + ubiquinone + H2O = acetate + CO2 + ubiquinol

740357, 741301, 724036, 724069

-

1.2.5.2

acetaldehyde + ubiquinone = acetate + ubiquinol

687166

-

1.2.5.3

CO + ubiquinone + H2O = CO2 + ubiquinol

736437, 736514

-

1.2.5.3

CO + ubiquinone-1 + H2O = CO2 + ubiquinol-1

735667

-

1.3.5.1

succinate + ubiquinone = fumarate + ubiquinol

391087, 391134, 391143, 391086, 655570, 685357, 391132, 391133, 654092, 655573, 656003, 657349, 671813, 674644, 685281, 696480, 391137, 391139, 674634, 654444, 656605, 687015, 687110, 687955, 687966, 688882, 688964, 689710, 724698, 657158, 391148, 654819, 655999, 656178, 656275, 656276, 685323, 2877, 391081, 391082, 391120, 391123, 391136, 391126, 391114, 391080, 391128, 762805, 742846, 762895, 391146, 674762, 672406, 686649, 687483, 687608

1zoy, 3D-view

1.3.5.1

succinate + ubiquinone = fumarate + ubiquinol

391087, 391134, 391143, 391086, 655570, 685357, 391132, 391133, 654092, 655573, 656003, 657349, 671813, 674644, 685281, 696480, 391137, 391139, 674634, 654444, 656605, 687015, 687110, 687955, 687966, 688882, 688964, 689710, 724698, 657158, 391148, 654819, 655999, 656178, 656275, 656276, 685323, 2877, 391081, 391082, 391120, 391123, 391136, 391126, 391114, 391080, 391128, 762805, 742846, 762895, 391146, 674762, 672406, 686649, 687483, 687608

5c3j, 3D-view

1.3.5.1

succinate + ubiquinone-1 = fumarate + ubiquinol

698658

1zoy, 3D-view

1.3.5.1

succinate + ubiquinone-1 = fumarate + ubiquinol

698658

5c3j, 3D-view

1.3.5.1

succinate + ubiquinone-1 = fumarate + ubiquinol-1

680599

1zoy, 3D-view

1.3.5.1

succinate + ubiquinone-1 = fumarate + ubiquinol-1

680599

5c3j, 3D-view

1.3.5.1

ubiquinone-1 + L-malate = ?

698668, 2877

1zoy, 3D-view

1.3.5.1

ubiquinone-1 + L-malate = ?

698668, 2877

5c3j, 3D-view

1.3.5.1

ubiquinone-1 + succinate = ubiquinol + fumarate

698668

1zoy, 3D-view

1.3.5.1

ubiquinone-1 + succinate = ubiquinol + fumarate

698668

5c3j, 3D-view

1.3.5.1

ubiquinone-1 + succinate = ubiquinol-1 + fumarate

698668

1zoy, 3D-view

1.3.5.1

ubiquinone-1 + succinate = ubiquinol-1 + fumarate

698668

5c3j, 3D-view

1.3.5.2

(S)-dihydroorotate + 2,3-dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone = orotate + reduced 2,3-dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone

740847

-

1.3.5.2

(S)-dihydroorotate + coenzyme Q1 = orotate + reduced coenzyme Q1

763072

-

1.3.5.2

dihydroorotate + coenzyme Q1 = orotate + reduced coenzyme Q1

696249

-

1.3.5.2

(S)-dihydroorotate + ubiquinone = orotate + reduced ubiquinone

740478

-

1.3.5.2

(S)-dihydroorotate + ubiquinone = orotate + ubiquinol

390925, 390924, 390922, 390926, 391224, 391226, 763351, 391235, 390929, 390919

-

1.2.5.3

2 entries

1.3.5.1

12 entries

1.3.5.2

5 entries

1.3.5.3

protoporphyrinogen IX + 3 ubiquinone = protoporphyrin IX + 3 ubiquinol

726366

-

1.3.98.1

dihydroorotate + 2,3-dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone = orotate + reduced 2,3-dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone

671050

-

1.3.98.1

dihydroorotate + ubiquinone-1 = orotate + ubiquinol-1

684848

-

1.4.5.1

D-Ala + oxidized coenzyme Q1 + H2O = pyruvate + NH3 + reduced coenzyme Q1

695533

-

1.4.5.1

D-alanine + oxidized coenzyme Q1 = pyruvate + NH3 + reduced coenzyme Q1

394971

-

1.4.5.1

D-Phe + oxidized coenzyme Q1 + H2O = phenylpyruvate + NH3 + reduced coenzyme Q1

695533

-

1.4.5.1

D-proline + oxidized coenzyme Q1 + H2O = DELTA1-pyrroline-2-carboxylate + NH3 + reduced coenzyme Q1

695533

-

1.4.5.1

D-Ser + oxidized coenzyme Q1 + H2O = 3-hydroxy-2-oxopropanoate + NH3 + reduced coenzyme Q1

695533

-

1.4.99.6

D-Pro + H2O + coenzyme Q1 = ?

695533

-

1.4.99.6

D-proline + H2O + coenzyme Q1 = DELTA1-pyrroline-2-carboxylate + NH3 + reduced coenzyme Q1

705545

-

1.5.5.1

reduced electron-transferring-flavoprotein + 6-isoprenylubiquinone = electron-transferring-flavoprotein + 6-isoprenylubiquinol

654538

-

1.5.5.1

reduced electron-transferring flavoprotein + coenzyme Q1 = electron-transferring flavoprotein + reduced coenzyme Q1

742902

-

1.5.5.1

reduced electron-transferring flavoprotein + ubiquinone = electron-transferring flavoprotein + ubiquinol

724446, 713271, 743186, 742306, 742902, 743249, 725063, 724410, 726447, 743809

-

1.5.5.1

reduced electron-transferring-flavoprotein + ubiquinone = electron-transferring-flavoprotein + ubiquinol

655306, 654538

-

1.5.5.1

semiquinone electron transferring flavoprotein + ubiquinone = electron-transferring flavoprotein + hydroquinone electron transferring flavoprotein + ubiquinol

392481

-

1.5.5.1

semiquinone electron transferring flavoprotein + ubiquinone Q1 = electron-transferring flavoprotein + hydroquinone electron transferring flavoprotein + ubiquinol Q1

392492

-

1.5.5.1

semiquinone electron-transferring flavoprotein + ubiquinone Q1 = electron-transferring flavoprotein + hydroquinone electron-transferring flavoprotein + ubiquinol Q1

392492

-

1.5.5.1

reduced electron-transferring flavoprotein-4'-deoxy-FAD + ubiquinone-1 = electron-transferring flavoprotein-4'-deoxy-FAD + ubiquinol-1

392490

-

1.5.5.3

L-proline + coenzyme Q1 = ?

741855

-

1.5.5.3

trans-4-hydroxy-L-proline + coenzyme Q1 = (3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate + ?

741855

-

1.3.98.1

2 entries

1.4.5.1

5 entries

1.4.99.6

2 entries

1.5.5.1

8 entries

1.5.5.3

2 entries

1.5.99.12

N6-(2-isopentenyl)adenine + coenzyme Q1 = adenine + 3-methylbut-2-enal + reduced coenzyme Q1

654539

-

1.5.99.B2

L-proline + coenzyme Q1 + H2O = DELTA1-pyrroline-5-carboxylate + reduced coenzyme Q1

724329

-

1.6.5.10

NADH + H+ + coenzyme Q1 = NAD+ + reduced coenzyme Q1

658899

-

1.6.5.10

NADPH + H+ + coenzyme Q1 = NADP+ + reduced coenzyme Q1

658899

-

1.6.5.10

NADPH + H+ + ubiquinone-1 = NADP+ + ubihydroquinone-1

392827

-

1.6.5.10

ubiquinone-1 + NADPH + H+ = ubiquinol-1 + NADP+

688840

-

1.6.5.2

coenzyme Q1 + NAD(P)H = reduced coenzyme Q1 + NADP+

688840

-

1.6.5.2

coenzyme Q1 + NADH = ?

680629

-

1.6.5.2

NADH + H+ + coenzyme Q1 = NAD+ + reduced coenzyme Q1

660483

-

1.6.5.2

NADH + H+ + ubiquinone = NAD+ + ubiquinone

700003

-

1.6.5.2

ubiquinone + NAD(P)H = reduced ubiquinone + NAD(P)+

694519

-

1.6.5.2

NADH + H+ + ubiquinone-1 = NAD+ + ubiquinol-1

700003

-

1.6.5.2

NADPH + H+ + ubiquinone-1 = NADP+ + ubiquinol-1

700003

-

1.6.5.2

ubiquinone-1 + NADPH + H+ = ubiquinol-1 + NADP+

392725

-

1.6.5.9

NADH + H+ + ubiquinone = NAD+ + ubiquinol

714296, 724488, 392700, 726384, 715710, 726096, 714305

-

1.6.5.9

NADH + H+ + ubiquinone-1 = NAD+ + ubiquinol-1

715052, 714189, 714884

-

1.6.5.10

4 entries

1.6.5.2

8 entries

1.6.5.9

2 entries

1.7.5.1

nitrite + ubiquinone + H2O = nitrate + ubiquinol

742333

-

1.8.1.4

ubiquinone + NAD(P)H = ubiquinol + NAD(P)+

658231, 658600

-

1.8.5.4

sulfide + coenzyme Q1 = sulfur + reduced coenzyme Q1

742905

-

1.8.5.4

sulfide + cysteine + coenzyme Q1 = cysteine persulfide + reduced coenzyme Q1

738630

-

1.8.5.4

sulfide + homocysteine + coenzyme Q1 = homocysteine persulfide + reduced coenzyme Q1

738630

-

1.8.5.4

sulfide + reduced glutathione + coenzyme Q1 = glutathione persulfide + reduced coenzyme Q1

738630

-

1.8.5.4

sulfide + ubiquinone = ? + ubiquinol

716170

-

1.8.5.4

2 sulfide + ubiquinone-1 = hydrogen disulfide + ubiquinol-1

724350

-

1.8.5.4

sulfide + cyanide + ubiquinone-1 = thiocyanate + ubiquinol-1

724350

-

1.8.5.4

sulfide + sulfite + ubiquinone-1 = thiosulfate + ubiquinol-1

724350

-

1.8.5.4

sulfide + ubiquinone-1 = sulfur + ubiquinol-1

714310, 714994, 724350, 727080

-

1.8.5.8

GSH + coenzyme Q1 = GSSG + reduced coenzyme Q1

744373

-

1.8.5.8

hydrogen sulfide + CoA + coenzyme Q1 = CoA-SSH + H+ + reduced coenzyme Q1

764431

-

1.8.5.8

hydrogen sulfide + coenzyme Q1 = hydrogen disulfide + reduced coenzyme Q1

744373

-

1.8.5.8

hydrogen sulfide + cysteine + coenzyme Q1 = ?

745313

-

1.8.5.8

hydrogen sulfide + glutathione + coenzyme Q1 = ?

744311

-

1.8.5.8

hydrogen sulfide + glutathione + coenzyme Q1 = glutathione persulfide + H+ + reduced coenzyme Q1

744373, 764431

-

1.8.5.8

hydrogen sulfide + glutathione + coenzyme Q1 = S-sulfanylglutathione + reduced coenzyme Q1

745313

-

1.8.5.8

hydrogen sulfide + homocysteine + coenzyme Q1 = ?

745313

-

1.8.5.8

hydrogen sulfide + sulfide + coenzyme Q1 = ?

745313

-

1.8.5.8

hydrogen sulfide + sulfite + coenzyme Q1 = thiosulfate + reduced coenzyme Q1

745313

-

1.8.5.8

Na2S + glutathione + coenzyme Q1 = S-sulfanylglutathione + reduced coenzyme Q1 + 2 Na+

764977

-

1.8.5.8

hydrogen sulfide + glutathione + ubiquinone = S-sulfanylglutathione + ubiquinol

764525

-

1.8.5.8

sulfide + ubiquinone = ?

745666

-

1.8.5.9

a [DsbA protein] with reduced L-cysteine residues + ubiquinone = a [DsbA protein] carrying a disulfide bond + ubiquinol

755706, 756115, 757693

-

1.8.5.9

a [DsbB protein] with reduced L-cysteine residues + ubiquinone = a [DsbB protein] carrying a disulfide bond + ubiquinol

756115

-

1.8.5.9

[DsbA protein] with reduced L-cysteine residues + ubiquinone = [DsbA protein] carrying a disulfide bond + ubiquinol

757146, 757516, 758211, 758288, 756589

-

1.8.5.9

[DsbB protein] with reduced L-cysteine residues + ubiquinone = [DsbB protein] carrying a disulfide bond + ubiquinol

757146, 756589

-

1.8.5.9

a [DsbA protein] with reduced L-cysteine residues + ubiquinone-1 = a [DsbA protein] carrying a disulfide bond + ubiquinol-1

757136

-

1.8.5.9

[DsbA protein] with reduced L-cysteine residues + ubiquinone-1 = [DsbA protein] carrying a disulfide bond + ubiquinol-1

758183, 758211, 756909

-

1.8.5.9

[DsbB protein] with reduced L-cysteine residues + ubiquinone-1 = [DsbB protein] carrying a disulfide bond + ubiquinol-1

756909

-

1.8.5.4

9 entries

1.8.5.8

13 entries

1.8.5.9

7 entries

1.8.99.B2

2 thiosulfate + ubiquinone = tetrathionate + ubiquinol

742121

-

7.1.1.2

NADH + 2,3-dimethoxy-5-methyl-6-isoprenyl-1,4-benzoquinone = NAD+ + ?

671827

7v2r, 3D-view

7.1.1.2

NADH + coenzyme Q1 + H+ = NAD+ + reduced coenzyme Q1

690388

7v2r, 3D-view

7.1.1.2

NADH + coenzyme Q1 = NAD+ + ?

658265

7v2r, 3D-view

7.1.1.2

NADH + H+ + coenzyme Q1 = NAD+ + reduced coenzyme Q1

658174, 659108, 659106

7v2r, 3D-view

7.1.1.2

NADH + oxidized coenzyme Q1 + 5 H+[side1] = NAD+ + reduced coenzyme Q1 + 4 H+[side2]

742879

7v2r, 3D-view

7.1.1.2

deamino-NADH + ubiquinone + H+[side 1] = deamino-NAD+ + ubiquinol + H+[side 2]

658135

7v2r, 3D-view

7.1.1.2

deamino-NADH + ubiquinone = deamino-NAD+ + ubiquinol

672349

7v2r, 3D-view

7.1.1.2

NADH + H+ + ubiquinone = NAD+ + ubiquinol

696270, 714993, 714303, 696380, 697166, 696147

7v2r, 3D-view

7.1.1.2

NADH + ubiquinone + 6 H+[side 1] = NAD+ + ubiquinol + 7 H+[side 2]

724420, 725142, 724310, 725443, 725517, 724252, 724383, 724564, 725003, 725491

7v2r, 3D-view

7.1.1.2

NADH + ubiquinone + H+ = NAD+ + ubiquinol

690427

7v2r, 3D-view

7.1.1.2

NADH + ubiquinone = ?

392717, 392692, 392705, 392711, 392707, 392714, 392700, 392701, 392681, 392690, 392723

7v2r, 3D-view

7.1.1.2

NADH + ubiquinone = NAD+ + ubiquinol

392685, 675345, 392680, 392706, 392710, 392717, 392718, 392683, 392701, 392704, 674305, 392722, 392719, 392678, 392681, 392682, 392692, 671940, 672008, 672041, 673620, 673940, 674624, 675494, 392697, 392693, 392694, 672348, 392679, 392700, 392708, 392709, 391082, 392676, 392677, 392684, 392691, 392699, 392703, 392721, 671827, 671993, 672129, 672176, 672291, 672597, 676868, 392687, 392688, 673524, 392698, 675654, 392690, 674467, 674521, 392696, 392702, 392720, 392724, 673551, 392686, 392723, 672403, 392705, 392711, 392707, 392714

7v2r, 3D-view

7.1.1.2

NADPH + H+ + ubiquinone = NADP+ + ubiquinol

696147, 673551

7v2r, 3D-view

7.1.1.2

NADPH + ubiquinone + 6 H+[side 1] = NADP+ + ubiquinol + 7 H+[side 2]

725443

7v2r, 3D-view

7.1.1.2

ubiquinone + NADH + H+ = ubiquinol + NAD+

692992

7v2r, 3D-view

7.1.1.2

NADH + H+ + ubiquinone-1 = NAD+ + ubiquinol-1

696270, 714281, 698670, 700003, 731312, 696700, 707505, 742028, 696510, 696312

7v2r, 3D-view

7.1.1.2

NADH + ubiquinone-1 + 5 H+[side 1] = NAD+ + ubiquinol-1 + 4 H+[side 2]

742759, 743066

7v2r, 3D-view

7.1.1.2

NADH + ubiquinone-1 + H+ = NAD+ + ubiquinol

690886

7v2r, 3D-view

7.1.1.2

NADH + ubiquinone-1 = NAD+ + reduced ubiquinone-1

674495

7v2r, 3D-view

7.1.1.2

NADH + ubiquinone-1 = NAD+ + ubiquinol-1

673940, 392722, 392831, 391082, 392691, 392717, 672327, 392696, 672657, 674533, 671370, 392827, 392686, 392723, 658167, 392677

7v2r, 3D-view

7.1.1.2

NADPH + H+ + ubiquinone-1 = NADP+ + ubiquinol-1

392683

7v2r, 3D-view

7.1.1.2

ubiquinone-1 + NADH + H+ = ubiquinol-1 + NAD+

394359, 392725

7v2r, 3D-view

7.2.1.1

deamino-NADH + H+ + ubiquinone + 2 Na+/in = deamino-NAD+ + ubiquinol + 2 Na+/out

711293

8evu, 3D-view

7.2.1.1

deamino-NADH + H+ + ubiquinone + 2 Na+/in = deamino-NAD+ + ubiquinol + 2 Na+/out

711293

8ew3, 3D-view

7.2.1.1

deamino-NADH + H+ + ubiquinone + n Na+/in = deamino-NAD+ + ubiquinol + n Na+/out

711991

8evu, 3D-view

7.2.1.1

deamino-NADH + H+ + ubiquinone + n Na+/in = deamino-NAD+ + ubiquinol + n Na+/out

711991

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + 2 Na+/in = NAD+ + ubiquinol + 2 Na+/out

711269, 711293

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + 2 Na+/in = NAD+ + ubiquinol + 2 Na+/out

711269, 711293

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + n Li+/in = NAD+ + ubiquinol + n Li+/out

725433

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + n Li+/in = NAD+ + ubiquinol + n Li+/out

725433

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + n Na+/in = NAD+ + ubiquinol + n Na+/out

724251, 742842, 710746, 713414, 725433, 725448, 725538, 711991, 711995, 711996, 711997, 725402, 725481, 725539, 712407

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + n Na+/in = NAD+ + ubiquinol + n Na+/out

724251, 742842, 710746, 713414, 725433, 725448, 725538, 711991, 711995, 711996, 711997, 725402, 725481, 725539, 712407

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + Na+/in = NAD+ + ubiquinol + Na+/out

712274

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone + Na+/in = NAD+ + ubiquinol + Na+/out

712274

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone = NAD+ + ubiquinol

700061, 698995, 696362

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone = NAD+ + ubiquinol

700061, 698995, 696362

8ew3, 3D-view

7.2.1.1

NADH + ubiquinone + Na+/in = NAD+ + ubiquinol + Na+/out

672293

8evu, 3D-view

7.2.1.1

NADH + ubiquinone + Na+/in = NAD+ + ubiquinol + Na+/out

672293

8ew3, 3D-view

7.2.1.1

NADH + ubiquinone = ?

392712, 392713, 392715, 392695, 392716

8evu, 3D-view

7.2.1.1

NADH + ubiquinone = ?

392712, 392713, 392715, 392695, 392716

8ew3, 3D-view

7.2.1.1

NADH + ubiquinone = NAD+ + ubiquinol

671141, 392695, 392716, 392712, 392713, 392715

8evu, 3D-view

7.2.1.1

NADH + ubiquinone = NAD+ + ubiquinol

671141, 392695, 392716, 392712, 392713, 392715

8ew3, 3D-view

7.2.1.1

thio-NADH + H+ + ubiquinone + 2 Na+/in = thio-NAD+ + ubiquinol + 2 Na+/out

711293

8evu, 3D-view

7.2.1.1

thio-NADH + H+ + ubiquinone + 2 Na+/in = thio-NAD+ + ubiquinol + 2 Na+/out

711293

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone 1 = NAD+ + ubiquinol 1

696362

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone 1 = NAD+ + ubiquinol 1

696362

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone-1 + n Li+/in = NAD+ + ubiquinol-1 + n Li+/out

725539

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone-1 + n Li+/in = NAD+ + ubiquinol-1 + n Li+/out

725539

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone-1 + n Na+/in = NAD+ + ubiquinol-1 + n Na+/out

711992, 711994, 725481, 725539, 658029, 725538, 725402

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone-1 + n Na+/in = NAD+ + ubiquinol-1 + n Na+/out

711992, 711994, 725481, 725539, 658029, 725538, 725402

8ew3, 3D-view

7.2.1.1

NADH + H+ + ubiquinone-1 = NAD+ + ubiquinol-1

696362, 696386, 699385

8evu, 3D-view

7.2.1.1

NADH + H+ + ubiquinone-1 = NAD+ + ubiquinol-1

696362, 696386, 699385

8ew3, 3D-view

7.2.1.1

NADH + ubiquinone-1 = NAD+ + ubiquinol-1

671351, 674274, 674705, 658029, 392695

8evu, 3D-view

7.2.1.1

NADH + ubiquinone-1 = NAD+ + ubiquinol-1

671351, 674274, 674705, 658029, 392695

8ew3, 3D-view

7.1.1.2

22 entries

7.2.1.1

32 entries

Product in Enzyme-catalyzed Reactions (40 results)

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Show Product (40 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.5.5

acetaldehyde + ubiquinol = ethanol + ubiquinone

0

-

1.1.5.5

citral + ubiquinol = ? + ubiquinone

0

-

1.1.5.5

citronellal + ubiquinol = citronellol + ubiquinone

0

-

1.10.3.11

2 ubiquinol + O2 = 2 ubiquinone + 2 H2O

0

-

1.10.3.11

2 ubiquinol-1 + O2 = 2 ubiquinone-1 + 2 H2O

0

-

1.10.3.11

ubiquinol + O2 = ubiquinone + H2O

0

-

1.10.3.11

ubiquinol-1 + O2 = ubiquinone-1 + H2O

0

-

1.1.5.5

3 entries

1.10.3.11

4 entries

1.10.3.17

2 O2 + ubiquinol = 2 superoxide + ubiquinone + 2 H+

0

-

1.10.5.1

nicotinamide riboside + reduced coenzyme Q1 = dihydronicotinamide riboside + coenzyme Q1

0

-

1.11.1.7

ubiquinol-1 + H2O2 = ubiquinone-1 + H2O

0

-

1.3.5.1

fumarate + quinol = succinate + ubiquinone

391137, 391139

1zoy, 3D-view

1.3.5.1

fumarate + quinol = succinate + ubiquinone

391137, 391139

5c3j, 3D-view

1.3.5.1

2 entries

1.5.5.1

electron-transferring flavoprotein + hydroquinone electron transferring flavoprotein + ubiquinol = semiquinone electron transferring flavoprotein + ubiquinone

0

-

1.6.5.2

NADH + H+ + ubiquinone = NAD+ + ubiquinone

0

-

1.7.5.1

nitrate + ubiquinol = nitrite + ubiquinone + H2O

0

-

1.8.1.4

3-nitrotyrosine + ubiquinol = 3-aminotyrosine + ubiquinone + H2O

0

-

1.8.1.4

8-nitroguanine + ubiquinol = 8-aminoguanine + ubiquinone + H2O

0

-

1.8.1.4

8-nitroxanthine + ubiquinol = 8-aminoxanthine + ubiquinone + H2O

0

-

7.1.1.3

2 ubiquinol + n H+ + O2 = 2 ubiquinone + n H+ + 2 H2O

0

-

7.1.1.3

ubiquinol + O2 + H+/in = ubiquinone + H2O + H+/out

0

-

7.1.1.3

ubiquinol + O2 + H+[side 1] = ubiquinone + H2O + H+[side 2]

0

-

7.1.1.3

ubiquinol-1 + O2 + H+/in = ubiquinone-1 + H2O + H+/out

0

-

7.1.1.3

ubiquinol-1 + O2 + H+[side 1] = ubiquinone-1 + H2O + H+[side 2]

0

-

1.8.1.4

3 entries

7.1.1.3

5 entries

7.1.1.5

ubiquinol-1 + O2 + H+[side 1] = ubiquinone-1 + H2O + H+[side 2]

0

-

7.1.1.7

2 ubiquinol + O2 + 4 H+[side 1] = 2 ubiquinone + 2 H2O + 4 H+[side 2]

0

-

7.1.1.7

ubiquinol + O2 + H+[side 1] = ubiquinone + H2O + H+[side 2]

0

-

7.1.1.8

coenzyme Q1H2 + 2 ferricytochrome c = coenzyme Q1 + 2 ferrocytochrome c + 2 H+

0

-

7.1.1.8

dihydroubiquinone + ferricytochrome c = ubiquinone + ferrocytochrome c + 2 H+

439947

-

7.1.1.8

ubiquinol + 2 4-carboxy-2,6-dinitrophenyllysine27-ferricytochrome c = ubiquinone + 2 4-carboxy-2,6-dinitrophenyllysine27-ferrocytochrome c + 2 H+

0

-

7.1.1.8

ubiquinol + 2 ferricyanide = ubiquinone + 2 ferrocyanide + 2 H+

0

-

7.1.1.8

ubiquinol + 2 ferricytochrome c = ubiquinone + 2 ferrocytochrome c + 2 H+

0

-

7.1.1.8

ubiquinol + 2 ferricytochrome c = ubiquinone + 2 ferrocytochrome c + 2 H+[side 2]

0

-

7.1.1.8

ubiquinol + 2 ferricytochrome c2 = ubiquinone + 2 ferrocytochrome c2 + 2 H+[side 2]

0

-

7.1.1.8

ubiquinol + 2 ferricytochrome c552 = ubiquinone + 2 ferrocytochrome c552 + 2 H+

0

-

7.1.1.8

ubiquinol + cytochrome c2 = ubiquinone + reduced cytochrome c2

0

-

7.1.1.8

ubiquinol + ferricytochrome b-561 = ubiquinone + ferrocytochrome b-561

0

-

7.1.1.8

ubiquinol + ferricytochrome b-562 = ubiquinone + ferrocytochrome b-562

0

-

7.1.1.8

ubiquinol + ferricytochrome c = ubiquinone + ferrocytochrome c

0

-

7.1.1.8

ubiquinol + ferricytochrome c = ubiquinone + ferrocytochrome c + H+

0

-

7.1.1.8

ubiquinol-1 + cytochrome c = ubiquinone-1 + reduced cytochrome c

0

-

7.1.1.7

2 entries

7.1.1.8

14 entries

Enzyme Cofactor/Cosubstrate (31 results)

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Show Cofactor (31 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.1.5.3

-

741302

-

1.1.5.4

-

722575, 723124

-

1.1.5.4

the route of electrons in this assay is unclear, but it probably leads from the enzyme either directly or via quinones to 2,6-dichlorophenol indophenol. The malate-dependent 2,6-dichlorophenol indophenol reduction rate catalyzed by Helicobacter pylori membranes could be stimulated by 30 to 50% by the addition of 60 mM ubiquinone-1. This suggests that quinones play, at least in part, an intermediary role in the reduction of the dye

287737

-

1.1.5.5

the enzyme has a high affinity ubiquinone binding site besides low-affinity ubiquinone reduction and ubiquinol oxidation sites. The bound ubiquinone in the ubiquinol site is involved in the electron transfer between heme c moieties and bulk ubiquinone or ubiquinol in the low affinity sites

685685

-

1.1.5.5

electrons extracted from ethanol at PQQ site are transferred to ubiquinone via heme c in subunit I and two of the three hemes c in subunit II

685310

-

1.1.99.20

electron acceptor

389904, 389908

-

1.1.99.20

in vivo electron acceptor

389904

-

1.1.5.4

2 entries

1.1.5.5

2 entries

1.1.99.20

2 entries

1.1.99.22

-

721866

-

1.1.99.6

possible physiological acceptor

287840

-

1.2.5.3

-

736437

-

1.2.5.3

-

736514

-

1.3.5.1

-

687015, 687110, 687955, 687966, 688964, 689710, 686649, 656275, 685323, 687608, 391082, 391123, 687483, 391080

1zoy, 3D-view

1.3.5.1

-

687015, 687110, 687955, 687966, 688964, 689710, 686649, 656275, 685323, 687608, 391082, 391123, 687483, 391080

5c3j, 3D-view

1.3.5.1

the residues required for quinone-binding are harbored by SdhD

686941

1zoy, 3D-view

1.3.5.1

the residues required for quinone-binding are harbored by SdhD

686941

5c3j, 3D-view

1.3.5.1

two putative binding sites in the di-heme membrane anchoring protein

685357

1zoy, 3D-view

1.3.5.1

two putative binding sites in the di-heme membrane anchoring protein

685357

5c3j, 3D-view

1.2.5.3

2 entries

1.3.5.1

6 entries

1.3.5.2

the mitochondrial enzyme requires oxidized ubiquinone, CoQ

712147

-

1.4.5.1

0.2 mM quinone stimulates reaction with D-alanine and oxidized 2,6-dichloroindophenol fold

394971

-

1.4.5.1

0.2 mM quinone stimulates reaction with D-alanine and oxidized 2,6-dichloroindophenol 25fold

394971

-

1.4.5.1

2 entries

1.5.5.1

-

743186, 742306, 742902, 743809, 743249

-

1.5.5.2

coenzyme Q1 is electron acceptor for PRODH/POX, which passes electrons directly to coenzyme Q1 (CoQ1) RODH/POX binds directly to CoQ1 without the formation of a tertiary complex. The transfer of electrons from proline to CoQ1 by PRODH/POX is dependent on downstream electron transfer from CoQ1 to Complexes III and IV

741588

-

1.7.5.1

-

742333

-

1.8.5.8

-

764525

-

1.8.99.B2

-

742121

-

5.3.4.1

tightly bound ubiquinone cofactor, which becomes oxidized to hydroquinone and is regenerated by the electron transport chain and O2PDI contains four transmembrane helices that surround the bound ubiquinone cofactor, overview

680746

-

7.1.1.2

-

714281, 714993

7v2r, 3D-view

7.1.1.8

-

439947, 439979, 440012, 440007

-

7.1.1.8

prosthetic group

440012

-

7.2.1.1

enzyme contains approximately one bound ubiquinone

392715

8evu, 3D-view

7.2.1.1

enzyme contains approximately one bound ubiquinone

392715

8ew3, 3D-view

7.1.1.8

2 entries

7.2.1.1

2 entries

Activator in Enzyme-catalyzed Reactions (2 results)

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Show Activating Compound (2 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.1.5.4

reduction of 2,6-dichlorophenol indophenol by solubilized enzyme is activated significantly by addition of the quinones decylubiquinone, duroquinone, 2-methyl-1,4-naphthoquinone (vitamin K3), ubiquinone-0 and ubiquinone-1. Optimal activation is observed with ubiquinone-1

287733

-

1.8.1.4

slight increase in activity might be due to formation of ubiquinol in the assay system

658431

-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

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Show Inhibitors (3 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.10.3.11

product inhibition, an excess amount of ubiquinol-2 is unable to suppress product inhibition with ubiquinone-1 therefore, the inhibition mode may not be competitive

725319

-

1.11.1.7

product inhibition, mixed-type

742809

-

2.2.1.6

-

740761

-

3D Structure of Enzyme-Ligand-Complex (PDB) (40 results)

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Show 3D Structure of Enzyme-Ligand-Complex (PDB) (40 entries)

EC NUMBER

ENZYME 3D STRUCTURE

1.10.2.2

2ybb, 3D-view

1.3.5.1

1zoy, 3D-view

1.3.5.1

5c3j, 3D-view

1.3.5.1

1zoy, 3D-view

1.3.5.1

5c3j, 3D-view

1.3.5.1

1zoy, 3D-view

1.3.5.1

5c3j, 3D-view

1.3.5.1

1zoy, 3D-view

1.3.5.1

5c3j, 3D-view

1.3.5.1

1zoy, 3D-view

1.3.5.1

5c3j, 3D-view

1.3.5.1

1zoy, 3D-view

1.3.5.1

5c3j, 3D-view

1.3.5.1

1zoy, 3D-view

1.3.5.1

5c3j, 3D-view

1.3.5.1

1zoy, 3D-view

1.3.5.1

5c3j, 3D-view

1.3.5.1

1zoy, 3D-view

1.3.5.1

5c3j, 3D-view

1.3.5.1

18 entries

1.6.99.5

2ybb, 3D-view

1.9.3.1

2ybb, 3D-view

7.1.1.2

7v2r, 3D-view

7.2.1.1

8evu, 3D-view

7.2.1.1

8ew3, 3D-view

7.2.1.1

8evu, 3D-view

7.2.1.1

8ew3, 3D-view

7.2.1.1

8evu, 3D-view

7.2.1.1

8ew3, 3D-view

7.2.1.1

8evu, 3D-view

7.2.1.1

8ew3, 3D-view

7.2.1.1

8evu, 3D-view

7.2.1.1

8ew3, 3D-view

7.2.1.1

8evu, 3D-view

7.2.1.1

8ew3, 3D-view

7.2.1.1

8evu, 3D-view

7.2.1.1

8ew3, 3D-view

7.2.1.1

8evu, 3D-view

7.2.1.1

8ew3, 3D-view

7.2.1.1

8evu, 3D-view

7.2.1.1

8ew3, 3D-view

7.2.1.1

18 entries

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (85 results)

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Show Turnover Number (85 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

1.1.5.5

76.3

-

using ethanol as cosubstrate, pH and temperature not specified in the publication

711032

1.1.99.18

43.5

-

pH 4.0, 30°C, wild-type enzyme

655002

1.1.99.18

44.2

-

pH 4.0, 30°C, recombinant enzyme

655002

1.3.5.1

1.7

-

mutant R28E/E29I, pH 8.0, 30°C

742846

1.3.5.1

10.7

-

mutant R81E, pH 8.0, 30°C

742846

1.3.5.1

11.6

-

pH 8.0, 25°C, recombinant subunit SDHB mutant G227L

685281

1.3.5.1

13.9

-

mutant R28L/E29L, pH 8.0, 30°C

742846

1.3.5.1

15.6

-

pH 8.0, 25°C, recombinant subunit SDHC mutant E101L

685281

1.3.5.1

16.2

-

pH 8.0, 25°C, recombinant subunit SDHC mutant D95L

685281

1.3.5.1

17.4

-

mutant R81A, pH 8.0, 30°C

742846

1.3.5.1

17.4

-

pH 8.0, 25°C, recombinant subunit SDHD mutant Q78L

685281

1.3.5.1

18.6

-

pH 7.0, 25°C, recombinant subunit SDHB/C mutant G227L/D95E

685281

1.3.5.1

19

-

mutant R28N, pH 8.0, 30°C

742846

1.3.5.1

19.3

-

mutant R28L, pH 8.0, 30°C

742846

1.3.5.1

20.9

-

pH 8.0, 25°C, recombinant subunit SDHC mutant E101D

685281

1.3.5.1

22.3

-

pH 8.0, 25°C, recombinant subunit SDHC mutant D95E

685281

1.3.5.1

24.8

-

pH 7.0, 25°C, recombinant subunit SDHB/C mutant G227L/D95L

685281

1.3.5.1

24.9

-

wild-type, pH 8.0, 30°C

742846

1.3.5.1

32.2

-

mutant R81K, pH 8.0, 30°C

742846

1.3.5.1

37.9

-

pH 8.0, 25°C, recombinant wild-type enzyme

685281

1.3.5.2

0.19

-

mutant Y528A, pH 8.0, 25°C

696249

1.3.5.2

1.5

-

mutant I272A, pH 8.0, 25°C

696249

1.3.5.2

1.9

-

mutant Y528F, pH 8.0, 25°C

696249

1.3.5.2

2.6

-

mutant F188A, pH 8.0, 25°C

696249

1.3.5.2

2.6

-

mutant F227A, pH 8.0, 25°C

696249

1.3.5.2

3.1

-

mutant R265A, pH 8.0, 25°C

696249

1.3.5.2

5.1

-

mutant L531A, pH 8.0, 25°C

696249

1.3.5.2

5.1

-

mutant Y528W, pH 8.0, 25°C

696249

1.3.5.2

7.3

-

mutant H185A, pH 8.0, 25°C

696249

1.3.5.2

7.8

-

wild-type, pH 8.0, 25°C

696249

1.1.99.18

2 entries

1.3.5.1

17 entries

1.3.5.2

10 entries

1.3.98.1

-999

-

at saturating concentration of dihydroorotate

671050

1.3.99.11

6.15

-

at saturating concentration of dihydroorotate

671050

1.5.5.1

33.5

-

-

392492

1.5.5.1

34.5

-

recombinant enzyme, pH 7.4, 25°C

654538

1.5.5.1

84

-

-

392487

1.5.5.1

115

-

-

391323, 392484

1.5.5.1

4 entries

1.5.5.3

0.19

-

at pH 7.5 and 25°C

741855

1.5.99.12

123.1

-

pH 6.5, recombinant enzyme

654539

1.5.99.B2

0.043

-

mutant enzyme G63A, at 23°C, in 50 mM potassium phosphate and 25 mM NaCl (pH 7.5)

724329

1.5.99.B2

0.046

-

mutant enzyme E64A, at 23°C, in 50 mM potassium phosphate and 25 mM NaCl (pH 7.5)

724329

1.5.99.B2

14

-

wild type enzyme, at 23°C, in 50 mM potassium phosphate and 25 mM NaCl (pH 7.5)

724329

1.5.99.B2

3 entries

1.6.5.2

6.4

-

pH 8.5, 60°C

680629

1.8.1.4

72

-

pH 7.5, 37°C, in absence of Zn2+

658600

1.8.1.4

300

-

pH 7.5, 37°C, in presence of Zn2+

658600

1.8.5.4

360

-

cosubstrates cyanide, sulfide, pH 8.5, 25°C

724350

1.8.5.4

364

-

cosubstrates sulfite, sulfide, pH 7.5, 25°C

724350

1.8.1.4

2 entries

1.8.5.4

2 entries

1.8.5.9

0.000007

-

at pH 8.0 and 30°C

757136

7.1.1.2

0.015

-

pH 8.0, 25°C

696700

7.1.1.2

211.5

-

-

658265

7.1.1.2

664

-

pH 7.0, 25°C

743066

7.2.1.1

57.7

-

mutant D397S, pH 8.0, temperature not specified in the publication

725539

7.2.1.1

58.8

-

mutant D397K, pH 8.0, temperature not specified in the publication, presence of 100 mM Na+

725539

7.2.1.1

59.7

-

mutant D397N, pH 8.0, temperature not specified in the publication

725539

7.2.1.1

59.8

-

mutant D397K, pH 8.0, temperature not specified in the publication, presence of 100 mM Li+

725539

7.2.1.1

61.3

-

mutant D397K, pH 8.0, temperature not specified in the publication

725539

7.2.1.1

61.9

-

mutant D397C, presence of 2-mercaptoethanol, pH 8.0, temperature not specified in the publication

725539

7.2.1.1

65.7

-

mutant D397C, pH 8.0, temperature not specified in the publication

725539

7.2.1.1

66

-

mutant D397E, pH 8.0, temperature not specified in the publication

725539

7.2.1.1

66.3

-

wild-type, pH 8.0, temperature not specified in the publication

725539

7.2.1.1

70.6

-

mutant D397A, pH 8.0, temperature not specified in the publication, presence of 100 mM Na+

725539

7.2.1.1

72.3

-

mutant D397A, pH 8.0, temperature not specified in the publication

725539

7.2.1.1

72.3

-

mutant D397A, pH 8.0, temperature not specified in the publication, presence of 100 mM Li+

725539

7.2.1.1

80.7

-

mutant D397S, pH 8.0, temperature not specified in the publication, presence of 100 mM Li+

725539

7.2.1.1

95.5

-

mutant D397N, pH 8.0, temperature not specified in the publication, presence of 100 mM Li+

725539

7.2.1.1

96.4

-

mutant D397E, pH 8.0, temperature not specified in the publication, presence of 100 mM Li+

725539

7.2.1.1

101.3

-

mutant D397S, pH 8.0, temperature not specified in the publication, presence of 100 mM Na+

725539

7.2.1.1

102.9

-

mutant D397C, pH 8.0, temperature not specified in the publication, presence of 100 mM Li+

725539

7.2.1.1

110.6

-

mutant D397C, presence of 2-mercaptoethanol, pH 8.0, temperature not specified in the publication, presence of 100 mM Li+

725539

7.2.1.1

122.9

-

mutant D397N, pH 8.0, temperature not specified in the publication, presence of 100 mM Na+

725539

7.2.1.1

129.6

-

mutant D397E, pH 8.0, temperature not specified in the publication, presence of 100 mM Na+

725539

7.2.1.1

152.9

-

mutant D397C, pH 8.0, temperature not specified in the publication, presence of 100 mM Na+

725539

7.2.1.1

162.2

-

mutant D397C, presence of 2-mercaptoethanol, pH 8.0, temperature not specified in the publication, presence of 100 mM Na+

725539

7.2.1.1

200

-

mutant G140A, pH 8.0, temperature not specified in the publication

725481

7.2.1.1

200

-

mutant G140A, pH 8.0, temperature not specified in the publication

725481

7.2.1.1

200

-

mutant G140L, pH 8.0, temperature not specified in the publication

725481

7.2.1.1

205.5

-

wild-type, pH 8.0, temperature not specified in the publication, presence of 100 mM Li+

725539

7.2.1.1

388

-

mutant G141V, pH 8.0, temperature not specified in the publication

725481

7.2.1.1

388

-

mutant G141V, pH 8.0, temperature not specified in the publication

725481

7.2.1.1

425

-

mutant G141A, pH 8.0, temperature not specified in the publication

725481

7.2.1.1

425

-

mutant G141A, pH 8.0, temperature not specified in the publication

725481

7.2.1.1

463

-

mutant G141L, pH 8.0, temperature not specified in the publication

725481

7.2.1.1

463

-

mutant G141L, pH 8.0, temperature not specified in the publication

725481

7.2.1.1

525

-

wild-type enzyme, pH 8.0, temperature not specified in the publication

725481

7.2.1.1

525

-

wild-type, pH 8.0, temperature not specified in the publication

725481

7.2.1.1

528.5

-

wild-type, pH 8.0, temperature not specified in the publication, presence of 100 mM Na+

725539

7.1.1.2

3 entries

7.2.1.1

35 entries