Ligand (+)-gallocatechin

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Basic Ligand Information

Molecular Structure
Picture of (+)-gallocatechin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C15H14O7
(+)-gallocatechin
XMOCLSLCDHWDHP-SWLSCSKDSA-N
Synonyms:
2,3-(trans)-(+)-gallocatechin, gallocatechin

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,3-(trans)-(+)-catechin + [reduced NADPH-hemoprotein reductase] + O2 = 2,3-(trans)-(+)-gallocatechin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-

Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,3-(trans)-(+)-catechin + [reduced NADPH-hemoprotein reductase] + O2 = 2,3-(trans)-(+)-gallocatechin + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
(2R,3R)-dihydromyricetin + NADPH = gallocatechin + NADP+ + H2O
show the reaction diagram
-
-
gallocatechin gallate + H2O = gallic acid + gallocatechin
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
50% inhibition at 0.28 mM
-
IC50: 0.000109 mM, expected to be useful for preventing and curing of Alzheimer‘s disease
-

Enzyme Kinetic Parameters

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.000109
-
IC50: 0.000109 mM, expected to be useful for preventing and curing of Alzheimer‘s disease

References & Links

Links to other databases for (+)-gallocatechin

ChEBI
PubChem
ChEBI
PubChem