Ligand 3-Mercaptopyruvate

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of 3-Mercaptopyruvate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H4O3S
3-Mercaptopyruvate
FBSFWRHWHYMIOG-UHFFFAOYSA-N
Synonyms:
2-Oxo-3-mercaptopropanoic acid, 2-oxo-3-thiopropanoate, 2-oxo-3-thiopropionic acid, 3-mercapto-2-oxo-propanoate, 3-Mercapto-2-oxopropanoate, 3-mercaptopyruvic acid, beta-Mercaptopyruvate, Mercaptopyruvate


Show all pahtways known for Show all BRENDA pathways known for 3-Mercaptopyruvate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-Cys + H2O + O2 = 2-oxo-3-mercaptopropanoic acid + NH3 + H2O2
show the reaction diagram
-
-
D-cysteine + H2O + O2 = 2-oxo-3-thiopropionic acid + NH3 + H2O2
show the reaction diagram
-
-
L-cysteine + 2-oxoglutarate = L-glutamate + beta-mercaptopyruvate
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (21 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-ornithine + 3-mercaptopyruvic acid + NADPH + H+ = ? + NADP+ + H2O
show the reaction diagram
-
L-glutamine + 3-mercaptopyruvate = 2-oxoglutaramate + L-cysteine
show the reaction diagram
-
cyanide + 3-mercaptopyruvate = ?
show the reaction diagram
-
3-mercaptopyruvate + activated tRNA = ? + S-tRNA
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (23 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-cysteine + H2O + NAD+ = 3-mercapto-2-oxopropanoate + NH3 + NADH
show the reaction diagram
-
-
L-cysteine + H2O + NAD+ = 3-mercapto-2-oxopropanoate + NH3 + NADH
show the reaction diagram
-
-
D-cysteine + H2O + O2 = 2-oxo-3-thiopropionic acid + NH3 + H2O2
show the reaction diagram
-
-
D-cysteine + H2O + methylene blue = 3-mercapto-2-oxopropanoate + NH3 + reduced methylene blue
show the reaction diagram
-
L-cysteine + H2O + 2 cytochrome b = 2-oxo-3-thiopropanoate + NH3 + 2 reduced cytochrome b
show the reaction diagram
-
-
L-cysteine + 2-oxoglutarate = 3-mercaptopyruvate + L-glutamate
show the reaction diagram
-
-
2-oxosuccinamic acid + L-cysteine = L-asparagine + 3-mercapto-2-oxopropanoate
show the reaction diagram
-
-
L-cysteine + 2-oxoglutarate = L-glutamate + beta-mercaptopyruvate
show the reaction diagram
-
L-cysteine + pyruvate = 3-mercapto-2-oxopropanoate + L-alanine
show the reaction diagram
-
-
L-cysteine + 2-oxoglutarate = 3-mercapto-2-oxopropanoate + L-glutamate
show the reaction diagram
-
cysteine + pyruvate = 3-mercapto-2-oxo-propanoate + L-alanine
show the reaction diagram
-
-
L-cysteine + 2-oxobutanoate = 2-aminobutanoate + 3-mercapto-2-oxopropanoate
show the reaction diagram
-
-
L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive inhibitor, supresses the transfer of sulfur to tRNA
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (22 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (39 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
4.8
-
pH 8.4, 37ºC
0.61
-
pH 7.0, 30°C, L-glutamine as amino group donor
0.0069
-
pH 7.8, 37°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.005
-
pH 7.8, 37°C

References & Links

Links to other databases for 3-Mercaptopyruvate

ChEBI
PubChem
-
PubChem