Ligand L-allo-isoleucine

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Basic Ligand Information

Molecular Structure
Picture of L-allo-isoleucine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H13NO2
L-allo-isoleucine
AGPKZVBTJJNPAG-UHNVWZDZSA-N
Synonyms:
alloisoleucine, L-alloisoleucine
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
L-allo-isoleucine + 2-oxoglutarate + O2 = (S)-3-hydroxy-L-allo-isoleucine + succinate + CO2
-
show the reaction diagram
alloisoleucine + H2O + NAD+ = 3-methyl-2-oxopentanoate + NADH + NH3
-
show the reaction diagram
L-2-aminoadipate + L-cysteine + L-allo-isoleucine + ATP = L-delta-(aminoadipyl)-L-cysteinyl-D-allo-isoleucine + AMP + diphosphate
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3D Structure of Enzyme-Ligand-Complex (PDB) (10 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
pH 7.5, 25°C, the assay measures the release of diphosphate by means of a coupled enzyme system in which diphosphate drives the reduction of NAD+ to NADH
0.0015
-

KM Value (2 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
pH 8.4, 25°C, 2-oxoglutarate as amino group acceptor
1.54
-
pH 7.5, 25°C, the assay measures the release of diphosphate by means of a coupled enzyme system in which diphosphate drives the reduction of NAD+ to NADH
0.04
-

References & Links

Links to other databases for L-allo-isoleucine

ChEBI
PubChem
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PubChem